Desperate for help and unsure whether traditional rescue efforts will come through, Harvey victims are using social media to share maps of their location and photos of themselves trapped on rooftops and inside buildings.

“Need help in NE Houston! Baby here and sick elderly!” one user posted on Twitter along with her address late Sunday.

Another woman, Alondra Molina, posted Monday on Facebook that her sister was desperate for a rescue for herself and her four children, including a 1-year-old.

“Please if someone could at least get them out of the city me and my mom will come get them,” Molina wrote on a Facebook group where dozens were pleading for help. “The roads are just all blocked and we can’t get in.”

Annette Fuller took a video when she began fearing for her life on Sunday. She was on the second floor of a neighbor’s home along with the residents of three other houses, including five children, as water rose and hit waist level on the first floor.

“We called 911 and it rang and rang and rang and rang,” Fuller said Monday after the water receded and she managed to return safely to her single-story home.

“There’s just no agency in the world that could handle Harvey,” she said. “However, none of us were warned that 911 might not work. It was very frightening.”

Fuller’s two daughters, who live in Austin and Dallas, posted her video to Facebook after their mother texted it to them, and the post went viral.

“Social media, in some ways, is more powerful than the government agencies,” Fuller said.

Nursing home rescue

A nursing home in Dickinson, a low-lying city 30 miles (48 kilometers) southeast of Houston, quickly became the face of the crisis after its owner took a photo of residents, some in wheelchairs, up to their chests in water.

The nursing home owner, Trudy Lampson, sent the photo to her daughter, whose husband posted it Sunday to Twitter, where it’s been retweeted about 4,500 times.

The photo was so dramatic that many users denounced it as fake. The nursing home residents were saved the same day.

“Thanks to all the true believers that re-tweeted and got the news organizations involved,” Lampson’s son-in-law, Timothy McIntosh, posted later in the day. “It pushed La Vita Bella to #1 on the priority list.”

McIntosh told The Associated Press on Monday that his post gained traction after a local newspaper reported it.

“We are in Tampa, Florida,” he said. “The only way we could have an impact was by trying to reach out to emergency services and trying to do social media to gain attention to the cause.”

Not only are the people who need rescuing relying on social media for help, volunteers and police departments alike are posting their phone numbers and instructions on Twitter and Facebook so people can get more immediate help.

Revolutionizing search and rescue

An unofficial battalion of volunteers called the Cajun Navy who brought small boats to Houston posted on Facebook that people who need rescuing should download the Zello cellphone app to find rescuers close to their area.

“This will connect you with officials on the ground there that can navigate help your way. PLEASE SHARE!” said the post, which has been shared more than 12,000 times since Sunday night.

Harris County Sheriff Ed Gonzalez tweeted early Sunday that a woman was going into labor and shared the address. An hour later, he updated his followers that the woman had been taken away in an ambulance.

More than any other natural disaster, Harvey has made it clear that social media has revolutionized the search-and-rescue process, said Karen North, a professor of social media at the University of Southern California.

“And what’s really fascinating is that this is not emergency services experts creating strategic systems to rescue people,” North said. “This is evolving organically … Not only can people reach out to 911 but to friends and family elsewhere who can not only reach out to 911 but directly to rescuers in the location where the person needs help.

“It’s really just the idea of taking technology designed for one purpose and applying them to a disaster situation,” North said.

Dozens of people continued to post their pleas to be rescued through late Monday.

Fuller said if the water rises again at her home, she won’t bother calling 911 and will post directly to social media.

“If I was desperate, I’d put it in a public Facebook site and say, `Somebody please help,’ and hope that somebody was looking,”‘ she said.
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In middle school, Junior Alvarado often struggled with multiplication and earned poor grades in math, so when he started his freshman year at Washington Leadership Academy, a charter high school in the nation’s capital, he fretted that he would lag behind.

But his teachers used technology to identify his weak spots, customize a learning plan just for him and coach him through it. This past week, as Alvarado started sophomore geometry, he was more confident in his skills.

“For me personalized learning is having classes set at your level,” Alvarado, 15, said in between lessons. “They explain the problem step by step, it wouldn’t be as fast, it will be at your pace.”

As schools struggle to raise high school graduation rates and close the persistent achievement gap for minority and low-income students, many educators tout digital technology in the classroom as a way forward. But experts caution that this approach still needs more scrutiny and warn schools and parents against being overly reliant on computers.

The use of technology in schools is part of a broader concept of personalized learning that has been gaining popularity in recent years. It’s a pedagogical philosophy centered around the interests and needs of each individual child as opposed to universal standards. Other features include flexible learning environments, customized education paths and letting students have a say in what and how they want to learn.

Personalized learning

Under the Obama administration, the Education Department poured $500 million into personalized learning programs in 68 school districts serving close to a half million students in 13 states plus the District of Columbia. Large organizations such as the Melinda and Bill Gates Foundation have also invested heavily in digital tools and other student-centered practices.

The International Association for K-12 Online Learning estimates that up to 10 percent of all America’s public schools have adopted some form of personalized learning. Rhode Island plans to spend $2 million to become the first state to make instruction in every one of its schools individualized. Education Secretary Betsy DeVos also embraces personalized learning as part of her broader push for school choice.

Supporters say the traditional education model, in which a teacher lectures at the blackboard and then tests all students at the same time, is obsolete and doesn’t reflect the modern world.

“The economy needs kids who are creative problem solvers, who synthesize information, formulate and express a point of view,” said Rhode Island Education Commissioner Ken Wagner. “That’s the model we are trying to move toward.”

At Washington Leadership Academy, educators rely on software and data to track student progress and adapt teaching to enable students to master topics at their own speed.

Digital tool finds problem

This past week, sophomores used special computer programs to take diagnostic tests in math and reading, and teachers then used that data to develop individual learning plans. In English class, for example, students reading below grade level would be assigned the same books or articles as their peers, but complicated vocabulary in the text would be annotated on their screen.

“The digital tool tells us: We have a problem to fix with these kids right here and we can do it right then and there; we don’t have to wait for the problem to come to us,” said Joseph Webb, founding principal at the school, which opened last year.

Webb, dressed in a green T-shirt reading “super school builder,” greeted students Wednesday with high-fives, hugs and humor. “Red boxers are not part of our uniform!” he shouted to one student, who responded by pulling up his pants.

The school serves some 200 predominantly African-American students from high-poverty and high-risk neighborhoods. Flags of prestigious universities hang from the ceiling and a “You are a leader” poster is taped to a classroom door. Based on a national assessment last year, the school ranked in the 96th percentile for improvement in math and in the 99th percentile in reading compared with schools whose students scored similarly at the beginning of the year.

It was one of 10 schools to win a $10 million grant in a national competition aimed at reinventing American high schools that is funded by Lauren Powell Jobs, widow of Apple founder Steve Jobs.

‘Female Bill Gates’

Naia McNatt, a lively 15-year-old who hopes to become “the African-American and female Bill Gates,” remembers feeling so bored and unchallenged in fourth grade that she stopped doing homework and her grades slipped.

At the academy, “I don’t get bored ‘cause I guess I am pushed so much,” said McNatt, a sophomore. “It makes you need to do more, you need to know more.”

In math class, McNatt quickly worked through quadratic equations on her laptop. When she finished, the system spitted out additional, more challenging problems.

Her math teacher, Britney Wray, says that in her previous school she was torn between advanced learners and those who lagged significantly. She says often she wouldn’t know if a student was failing a specific unit until she started a new one.

In comparison, the academy’s technology now gives Wray instant feedback on which students need help and where. “We like to see the problem and fix the problem immediately,” she said.

Still, most researchers say it is too early to tell if personalized learning works better than traditional teaching.

A recent study by the Rand Corporation found that personalized learning produced modest improvements: a 3 percentile increase in math and a smaller, statistically insignificant increase for reading compared with schools that used more traditional approaches. Some students also complained that collaboration with classmates suffered because everybody was working on a different task.

“I would not advise for everybody to drop what they are doing and adopt personalized learning,” said John Pane, a co-author of the report. “A more cautious approach is necessary.”

New challenges

The new opportunities also pose new challenges. Pediatricians warn that too much screen time can come at the expense of face-to-face social interaction, hands-on exploration and physical activity. Some studies also have shown that students may learn better from books than from computer screens, while another found that keeping children away from computers for five days in a row improved their emotional intelligence.

Some teachers are skeptical. Marla Kilfoyle, executive director of the Badass Teachers Association, an education advocacy group, agrees that technology has its merits, but insists that no computer or software should ever replace the personal touch, motivation and inspiration teachers give their students.

“That interaction and that human element is very important when children learn,” Kilfoyle said.

 
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Ever so slowly, the world is edging towards the demise of the gasoline-powered engine. It likely won’t come for decades, but it’s coming. Two new entries in the alternative powered vehicle department are showing off ways that technology is slowly changing the automobile marketplace. VOA’s Kevin Enochs reports
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Iranian media are reporting that Apple Inc. has removed all Iranian mobile apps from its App Store.

In reaction to Apple’s decision, Telecommunication Minister Mohammad Javad Azari Jahromi said Apple should respect its Iranian consumers. He also sent out this tweet:

Apple, based in Cupertino, California, did not immediately respond to a request for comment.

Jahromi tweeted: “11 percent of Iran’s mobile phone market share is owned by Apple. Giving respect to consumer rights is a principle today which Apple has not followed. We will follow up the cutting of the apps legally.”

Apple is not officially in Iran or any other Persian Gulf countries, but many Iranians purchase its products from stores inside Iran.
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People smugglers are using Facebook to broadcast the abuse and torture

of migrants in order to extort ransom money from their families, the U.N. migration agency said on Friday.

The International Organization for Migration (IOM) lambasted the tech giant for failing to police the platform and help crack down on traffickers.

One video hosted on the site since June shows Libyan gangmasters threatening emaciated and abused migrants – mostly Somalis and Ethiopians – huddled in a concrete room.

IOM said the traffickers had sent clips to the captives’ families via the encrypted messaging service WhatsApp – a Facebook channel – along with threats that their loved ones would be killed unless ransoms of up to $10,000 were paid.

One young Somali man is seen lying face down with a concrete block on his back. “I was asked for $8,000,” he says, according to the IOM. “They broke my teeth. They broke my hand. I have been here 11 months. They put this stone on me for the last three days. It’s really painful.”

British newspaper The Times, which ran the story on its front page on Friday, also quoted a young Ethiopian who had been held for 15 months. “They beat me with iron bars,” he said. “They ordered me to pay $8,300 and my family cannot afford to pay that amount.”

Hundreds of thousands of refugees and migrants have crossed the Mediterranean from North Africa to Europe since 2014, and thousands have died trying.

Facebook, which has also been criticized for failing to stop traffickers using the platform to advertise their services, said posts by smuggling groups would be removed if reported.

“We encourage people to keep using our reporting tools to flag this kind of behavior so it can be reviewed and swiftly removed by our global team of experts, who work with law enforcement agencies around the world,” a spokesperson said.

But Facebook said it had not removed the June video as it had been posted by a Somali journalist and was important for raising awareness of the problem.

However, IOM spokesman Leonard Doyle accused Facebook of “arrant nonsense”, adding that the smugglers had used the journalist to publicize their demands.

He told the Thomson Reuters Foundation it was totally inappropriate for Facebook to host a video showing the faces of vulnerable people being abused.

“Don’t let Facebook off the hook here,” he said. “It’s an absolutely nonsensical argument that it’s up to the public to notify Facebook of stuff that’s happening on Facebook.

“They should invest heavily in policing their platforms to stop vulnerable migrants being exploited, extorted and murdered.”

Doyle said the IOM had tried without success to talk to Facebook about targeting smugglers.

“They should stop smugglers telling people there’s an El Dorado waiting for them in Europe when it’s a lie,” he added. “It’s not good enough to say, ‘we are a technology platform, it’s got nothing to do with us’.”

Doyle said the IOM had tried to find the people in the video, but they had disappeared.

 
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Tesla next month plans to unveil an electric big-rig truck with a working range of 200 to 300 miles, Reuters has learned, a sign that the electric car maker is targeting regional hauling for its entry into the commercial freight market.

Chief Executive Elon Musk has promised to release a prototype of its Tesla Semi truck next month in a bid to expand the company’s market beyond luxury cars. The entrepreneur has tantalized the trucking industry with the prospect of a battery-powered heavy-duty vehicle that can compete with conventional diesels, which can travel up to 1,000 miles on a single tank of fuel.

Tesla’s electric prototype will be capable of traveling the low end of what transportation veterans consider to be “long-haul” trucking, according to Scott Perry, an executive at Miami-based fleet operator Ryder System. Perry said he met with Tesla officials earlier this year to discuss the technology at the automaker’s manufacturing facility in Fremont, California.

Perry said Tesla’s efforts are centered on an electric big-rig known as a “day cab” with no sleeper berth, capable of traveling about 200 to 300 miles with a typical payload before recharging.

“I’m not going to count them out for having a strategy for longer distances or ranges, but right out of the gate I think that’s where they’ll start,” said Perry, who is the chief technology officer and chief procurement officer for Ryder.

Tesla responded to Reuters questions with an email statement saying, “Tesla’s policy is to always decline to comment on speculation, whether true or untrue, as doing so would be silly. Silly!”

Tesla’s plan, which could change as the truck is developed, is consistent with what battery researchers say is possible with current technology. Tesla has not said publicly how far its electric truck could travel, what it would cost or how much cargo it could carry. But Musk has acknowledged that Tesla has met privately with potential buyers to discuss their needs.

Reuters reported earlier this month that Tesla is developing self-driving capability for the big rig.

‘Manufacturing hell’

Musk has expressed hopes for large-scale production of the Tesla Semi within a couple of years. That audacious effort could open a potentially lucrative new market for the Palo Alto, California-based automaker.

Or it could prove an expensive distraction. Musk in July warned that the company is bracing for “manufacturing hell” as it accelerates production of its new Model 3 sedan. Tesla aims to produce 5,000 of the cars per week by the end of this year, and 10,000 per week sometime next year.

Tesla shares are up about 65 percent this year. But skeptics abound. Some doubt Musk’s ability to take Tesla from a niche producer to a large-scale automaker. About 22 percent of shares available for trade have been sold “short” by investors who expect the stock to fall.

Musk, a quirky billionaire whose transportation ambitions include colonizing the planet Mars, has long delighted in defying conventional wisdom. At Tesla’s annual meeting in June, he repeated his promise of a battery-powered long-haul big rig.

“A lot of people don’t think you can do a heavy-duty, long-range truck that’s electric, but we are confident that this can be done,” he said.

Trucking’s sweet spot

While the prototype described by Ryder’s Perry would fall well short of the capabilities of conventional diesels, Musk may well have found a sweet spot if he can deliver. Roughly 30 percent of U.S. trucking jobs are regional trips of 100 to 200 miles, according to Sandeep Kar, chief strategy officer of Toronto-based Fleet Complete, which tracks and analyzes truck movement.

A truck with that range would be able to move freight regionally, such as from ports to nearby cities or from warehouses to retail establishments.

“As long as [Musk] can break 200 miles, he can claim his truck is ‘long haul’ and he will be technically right,” Kar said.

Interest in electric trucks is high among transportation firms looking to reduce their emissions and operating costs.

Electric motors require less maintenance than internal combustion engines. Juice from the grid is cheaper than diesel.

But current technology doesn’t pencil when it comes to powering U.S. trucks across the country. Experts say the batteries required would be so large and heavy there would be little room for cargo.

An average diesel cab costs around $120,000. The cost of the battery alone for a big rig capable of going 200 to 400 miles carrying a typical payload could be more than that, according to battery researchers Shashank Sripad and Venkat Viswanathan of Carnegie Mellon University.

Battery weight and ability would limit a semi to a range of about 300 miles with an average payload, according to a paper recently published by Viswanathan and Sripad. The paper thanked Tesla for “helpful comments and suggestions.” Tesla did not endorse the work or comment on the conclusions to Reuters.

A range of 200 to 300 miles would put Tesla at the edge of what the nascent electric truck industry believes is economically feasible, the researchers and industry insiders said.

Short-haul trucks

Transportation stalwarts such as manufacturer Daimler AG and shipping company United Parcel Service said they are focusing their electric efforts on short-haul trucks. That’s because smaller distances and lighter payloads require less battery power, and trucks can recharge at a central hub overnight.

Daimler, the largest truck manufacturer in the world by sales, will begin production this year on an electric delivery truck. The vehicle will have a 100-mile range and be capable of carrying a payload of 9,400 pounds, about 1,000 pounds less than its diesel counterpart, according to Daimler officials.

Daimler has been joined by a handful of startups such as Chanje, a Los Angeles-based manufacturer that has a partnership with Ryder to build 100-mile-range electric trucks for package delivery.

Ryder and its customers believe electric trucks could cost more to buy but may be cheaper to maintain and have more predictable fuel costs. As batteries become cheaper and environmental regulation increases, the case for electric trucks could strengthen.

“This tech is being seen as a major potential differentiator. Everyone wants to understand how real it is,” said Perry, the chief technology officer.
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A new, high-tech yarn that generates electricity when stretched or twisted could use ocean waves and human motion to lower man’s dependency on fossil fuels, researchers said Thursday.

An international team of scientists said in a study they had developed a stretchy yarn made of carbon nanotubes — tiny strands of carbon atoms up to 10,000 times smaller than a hair — that produces electricity from a host of natural sources.

“The easiest way to think of twistron harvesters is you have a piece of yarn, you stretch it, and out comes electricity,” said Carter Haines, a lead author of the study published in the journal Science. The device, which exploits the ability of nanotubes to transfer springlike motion into electrical energy, has numerous possible applications, according to the paper.

In the lab, tests showed that yarn weighing less than a housefly could light up a small LED.

When sewn into a T-shirt, it could power breathing sensors — like those used to monitor babies — using the stretch caused by the chest expanding at every inhalation.

The innovation could be used to power internet-connected devices and smart clothing, said the study’s senior author, Ray Baughman, a professor at the University of Texas-Dallas.

“Electronic textiles are of major commercial interest, but how are you going to power them?” Baughman said in a statement.

“Harvesting electrical energy from human motion is one strategy for eliminating the need for batteries,” he said.

Seawater operation

But the twistron’s most compelling feature was the ability to operate in seawater and potentially harvest vast amounts of energy from the ocean, he added.

“The grander dream is to make a real difference in the energy economy of nations,” Baughman told the Thomson Reuters Foundation by phone.

A trial in South Korea showed that a small twistron attached between a buoy and a sinker on the seabed produced electricity every time a passing wave pulled it.

Baughman said that the technique could be scaled up in the future to create sea-power stations that can light entire cities, though harvesters are currently too expansive.

Under the Paris accord reached in 2015, rich and poor countries committed to reducing emissions of greenhouse gases generated by burning fossil fuels that are blamed by scientists for warming the planet.
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Britain will set out a plan to cooperate closely with Europe on data protection rules after it leaves the European Union, hoping to reassure businesses and law enforcement agencies that there will be no disruption to exchanges of information.

Minister for Digital Matt Hancock said Britain was leading the way on data protection laws and had worked closely with its EU partners in developing standards.

“We want the secure flow of data to be unhindered in the future as we leave the EU,” he said. “So a strong future data relationship between the U.K. and EU, based on aligned data protection rules, is in our mutual interest.”

In the latest paper looking at its future relationship with the EU, the British government said it would outline Thursday how it wanted collaboration in data security to continue.

Privacy, flexibility

“Our goal is to combine strong privacy rules with a relationship that allows flexibility, to give consumers and businesses certainty in their use of data,” Hancock said.

Noting that the digital economy in Britain was worth 118.4 billion pounds ($151.5 billion) in 2015, he said any disruption in the free flow of data could be costly both to Britain and to the remaining members of the bloc.

British lawmakers said last month the country could be put at a competitive disadvantage and the police could lose access to intelligence if the government failed to retain unhindered flows of data.

Britain has published a number of papers this month to try to nudge negotiations with the EU on Brexit forward, tackling subjects such as laws, customs and the border between Ireland and Northern Ireland.
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Els van der Heijden, who has cystic fibrosis, was finding it ever harder to breathe as her lungs filled with thick, sticky mucus. Despite taking more than a dozen pills and inhalers a day, the 53-year-old had to stop working and scale back doing the thing she loved best, horseback riding.

Doctors saw no sense in trying an expensive new drug because it hasn’t been proven to work in people with the rare type of cystic fibrosis that van der Heijden had.

Instead, they scraped a few cells from van der Heijden and used them to grow a mini version of her large intestine in a petri dish. When van der Heijden’s “mini gut” responded to treatment, doctors knew it would help her too.

“I really felt, physically, like a different person,” van der Heijden said after taking a drug — and getting back in the saddle.

Someday for transplants?

This experiment to help people with rare forms of cystic fibrosis in the Netherlands aims to grow mini intestines for every Dutch patient with the disease to figure out, in part, what treatment might work for them. It’s an early application of a technique now being worked on in labs all over the world, as researchers learn to grow organs outside of the body for treatment — and maybe someday for transplants.

So far, doctors have grown mini guts — just the size of a pencil point — for 450 of the Netherlands’ roughly 1,500 cystic fibrosis patients.

“The mini guts are small, but they are complete,” said Dr. Hans Clevers of the Hubrecht Institute, who pioneered the technique. Except for muscles and blood vessels, the tiny organs “have everything you would expect to see in a real gut, only on a really small scale.”

These so-called organoids mimic features of full-size organs, but don’t function the same way. Although many of the tiny replicas are closer to undeveloped organs found in an embryo than adult ones, they are helping scientists unravel how organs mature and providing clues on how certain diseases might be treated.

Mini kidneys in Australia

 In Australia, mini kidneys are being grown that could be used to test drugs. Researchers in the U.S. are experimenting with tiny bits of livers that might be used to boost failing organs. At Cambridge University in England, scientists have created hundreds of mini brains to study how neurons form and better understand disorders like autism. During the height of the Zika epidemic last year, mini brains were used to show the virus causes malformed brains in babies.

In the Netherlands, the mini guts are used as a stand-in for cystic fibrosis patients to see if those with rare mutations might benefit from a number of pricey drugs, including Orkambi. Made by Vertex Pharmaceuticals, Orkambi costs about 100,000 euros per patient every year in some parts of Europe, and it’s more than double that in the U.S., which approved the drug in 2015. Despite being initially rejected by the Dutch government for being too expensive, negotiations with Vertex were reopened in July.  

Making a single mini gut and testing whether the patient would benefit from certain drugs costs a couple of thousand euros. The program is paid for by groups including health insurance companies, patient foundations and the government. The idea is to find a possible treatment for patients, and avoid putting them on expensive drugs that wouldn’t work for them.

About 50 to 60 patients across the Netherlands have been treated after drugs were tested on organoids using their cells, said Dr. Kors van der Ent, a cystic fibrosis specialist at the Wilhelmina Children’s Hospital, who leads the research.

Mutations in single gene

Clevers made a discovery about a decade ago that got researchers on their way. They found pockets of stem cells, which can turn into many types of other cells, in the gut. They then homed in a growing environment in the lab that spurred these cells to reproduce rapidly and develop.  

“To our surprise, the stem cells started building a mini version of the gut,” Clevers recalled.  

Cystic fibrosis is caused by mutations in a single gene that produces a protein called CFTR, responsible for balancing the salt content of cells lining the lungs and other organs.

To see if certain drugs might help cystic fibrosis patients, the medicines are given to their custom-made organoids in the lab. If the mini organs puff up, it’s a sign the cells are now correctly balancing salt and water. That means the drugs are working, and could help the patient from whom the mini gut was made.

Mini organs vs. cancer

Researchers are also using the mini guts to try another approach they hope will someday work in people — using a gene editing technique to repair the faulty cystic fibrosis gene in the organoid cells.

Other experiments are underway in the Netherlands and the U.S. to test whether organoids might help pinpoint treatments for cancers involving lungs, ovaries and pancreas.

While the idea sounds promising, some scientists said there are obstacles to using mini organs to study cancer.

Growing a mini cancer tumor, for example, would be far more challenging because scientists have found it difficult to make tumors in the lab that behave like in real life, said Mathew Garnett of the Wellcome Trust Sanger Institute, who has studied cancer in mini organs but is not connected to Clevers’ research.

Huge hurdles remain

Also, growing the cells and testing them must happen faster for cancer patients who might not have much time to live, he said.

Meanwhile, Clevers wants to one day make organs that are not so mini.

“My dream would be to be able to custom-make organs,” he said, imagining a future where doctors might have a “freezer full of livers” to choose from when sick patients arrive.

Others said while such a vision is theoretically possible, huge hurdles remain.

“There are still enormous challenges in tissue engineering with regards to the size of the structure we’re able to grow,” said Jim Wells, a pediatrics professor at the Cincinnati Children’s Hospital Medical Center. He said the mini organs are far smaller than what would be needed to transplant into people and it’s unclear if scientists can make a working, life-sized organ in the lab.

Complex interplay

There are other limitations to growing miniature organs in a dish, said Madeline Lancaster at Cambridge University.  

“We can study physical changes and try to generate drugs that could prevent detrimental effects of disease, but we can’t look at the complex interplay between organs and the body,” she said.

For patients like van der Heijden, who was diagnosed with cystic fibrosis as a toddler, the research has helped her regain her strength. Vertex agreed to supply her with the drug.

“It was like somebody opened the curtains and said, ‘Sunshine, here I am, please come out and play.’” she said. “It’s strange to think this is all linked to some of my cells in a lab.”
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The U.S. Defense Department is making another multimillion-dollar investment in high-energy lasers that have the potential to destroy enemy drones and mortars, disrupt communication systems and provide military forces with other portable, less costly options on the battlefield.

U.S. Senator Martin Heinrich, a New Mexico Democrat who sits on the Senate Armed Services Committee and is a longtime supporter of directed-energy research, announced the $17 million investment during a news conference Wednesday inside a Boeing lab where many of the innovations were developed.

The U.S. already has the ability to shoot down enemy rockets and take out other threats with traditional weapons, but Heinrich said it’s expensive.

High-energy lasers and microwave systems represent a shift to weapons with essentially endless ammunition and the ability to wipe out multiple threats in a short amount of time, he said.

“This is ready for prime time,” Heinrich, who has an engineering degree, said of the concept.

Boeing has been working on high-energy laser and microwave weapons systems for years. The effort included a billion-dollar project to outfit a 747 with a laser cannon that could shoot down missiles while airborne. The system was complex and filled the entire back half of the massive plane.

Size of a suitcase

With advancements over the past two decades, high-powered laser weapons systems can now fit into a large suitcase for transport across the battlefield or be mounted to a vehicle for targeting something as small as the device that controls the wings of a military drone.

“Laser technology has moved from science fiction to real life,” said Ron Dauk, head of Boeing’s Albuquerque site.

The company’s compact laser system has undergone testing by the military, and engineers are working on a higher-powered version for testing next year.

While the technology has matured, Dauk and Heinrich said the exciting part is that it’s on the verge of moving from the lab to the battlefield.

Another $200 million has been requested in this year’s defense appropriations bill that would establish a program within the Pentagon for accelerating the transition of directed-energy research to real applications.

Heinrich said continued investment in such projects will help solidify New Mexico’s position as a leading site of directed-energy research and bring more money and high-tech jobs to the state.

Boeing already contributes about $120 million to the state’s economy through its contracts with vendors.
…

Protecting people rather than property or animals will be the priority under pioneering new German legal guidelines for the operation of driverless cars, the transport ministry said on Wednesday.

Germany is home to some of the world’s largest car companies, including Volkswagen, Daimler and BMW, all of which are investing heavily in self-driving technology.

German regulators have been working on rules for how such vehicles should be programmed to deal with a dilemma, such as choosing between hitting a cyclist or accelerating beyond legal speeds to avoid an accident.

Under new ethical guidelines — drawn up by a government-appointed committee comprising experts in ethics, law and technology — the software that controls such cars must be programmed to avoid injury or death of people at all cost.

That means that when an accident is unavoidable, the software must choose whichever action will hurt people the least, even if that means destroying property or hitting animals in the road, a transport ministry statement showed.

The software may not decide on its course of action based on the age, sex or physical condition of any people involved.

“The interactions of humans and machines is throwing up new ethical questions in the age of digitalization and self-learning systems,” German Transport Minister Alexander Dobrindt said in a a statement.

“The ministry’s ethics commission has pioneered the cause and drawn up the world’s first set of guidelines for automated driving,” he added.

Germany earlier this year passed legislation under which a driver must be sitting behind the wheel at all times ready to take back control if prompted to do so by the autonomous vehicle, clearing the way for the development and testing of self-driving cars.
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Samsung Electronics set out to wipe the slate clean in New York on Wednesday with a new Galaxy Note 8 phablet, hoping features such as dual rear cameras and its biggest-ever screen will extinguish memories of its fire-prone predecessor.

The world’s largest smartphone maker by market share has put safety at the center of a phone-cum-tablet that is likely to compete for pre-holiday season sales with a widely expected 10th anniversary iPhone from U.S. rival Apple Inc.

The unveiling comes five months after the release of the Galaxy S8 smartphone. Analysts said brisk sales of that device indicate recovery in Samsung’s standing, after battery fires prompted the October withdrawal of the Galaxy Note 7 just two months into sales at an opportunity cost of $5.48 billion.

The fires briefly lost Samsung its No. 1 rank, showed data from researcher Counterpoint. It has since regained ground, with Strategy Analytics putting its April-June share at 22 percent — more than Apple and China’s Huawei Technologies Co Ltd combined.

Cumulative sales of the S8 and S8+, released in the period, were 15 percent over those of the S7, Samsung said in July.

Samsung’s Note series usually sport bigger screens than the S series and come equipped with a removable stylus. The trademark curved screen of the latest incarnation measures 6.3 inches corner to corner, a mere 0.1 inch bigger than the S8+.

The South Korean firm has been a principle driver of growth in handsets with 6 inch-plus screens, a category which Strategy Analytics expects to grow 10 times faster than the overall market next year.

Samsung has also installed dual rear cameras on a handset for the first time, adding the Note 8 to a trend which promises improved photographic control and picture quality.

Other features include security technology, such as facial recognition and fingerprint and iris scanning, and artificial intelligence in the form of Samsung’s Bixby voice-command assistant.

The Note 8 will be sold from mid-September, Samsung said, without elaborating on place or price.
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