The World Health Organization has chosen Ghana, Kenya and Malawi as the countries where the world’s first malaria vaccine will be tested next year on young children.

The injectable vaccine, known as RTS,S, or Mosquirix, was developed by the British pharmaceutical company, GlaxoSmithKline.

The test will be conducted on babies and toddlers, aged 5 to 17 months.

Malaria is a life-threatening disease caused by parasites that are transmitted to people through the bites of infected female mosquitoes.

WHO said in a statement the pilot program “will assess the feasibility of delivering the required four doses of RTS,S, the vaccine’s potential role in reducing childhood deaths, and its safety in routine use.

“The prospect of a malaria vaccine is great news. Information gathered in the pilot will help us make decisions on the wider use of this vaccine,” said Dr. Matshidiso Moeti, WHO Regional Director for Africa. “Combined with existing malaria interventions, such a vaccine would have the potential to save tens of thousands of lives in Africa.”

Malaria interventions include insecticide-treated nets and spraying indoor walls with insecticides.

In 2015, approximately 429,000 people died from malaria, the majority of them were young children in Africa.

Global efforts between 2000 and 2015, however, have led to a 62 percent reduction in malaria deaths.

According to WHO, “Africa bears the greatest burden of malaria worldwide.” In 2015, sub-Saharan Africa was home to 90 percent of malaria cases and 92 percent of malaria deaths.

Tuesday is World Malaria Day.
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From: MeNeedIt

European shares opened sharply higher and the euro briefly vaulted to five-month peaks on Monday after the market’s favored candidate won the first round of the French election, reducing the risk of another Brexit-like shock.

The victory for pro-EU centrist Emmanuel Macron, who is now expected to beat right-wing rival Marine Le Pen in a deciding vote next month, sent the pan-European STOXX 50 index up 3 percent, France’s CAC40 almost 4 percent and bank stocks more than 6 percent.

Traders top-sliced some of the euro’s overnight gains, but it was still up more than 1 percent on the dollar, more than 2 percent against the yen and 1.3 percent on the pound as the early flurry of deals subsided.

“It (the first round result) has come out in line with the market’s expectations so you have something of a risk rally as there was a bit of a risk-premium built into all markets,” said James Binny, head of currency at State Street Global Advisors.

There was also an unwinding of safe-haven trades.

Shorter-term German bonds saw their biggest sell-off since the end of 2015 as investors piled back into French as well as Italian, Spanish, Portuguese and Greek debt.

The Japanese yen’s fall was widespread, the market’s so-called fear-guage, the VIX volatility index, plunged the most since November and gold saw its biggest tumble in more than a month.

E-mini futures for Wall Street’s S&P 500 climbed 0.9 percent in early trade, while yields on 10-year U.S. Treasury notes rose almost 8 basis points to 2.31 percent.
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From: MeNeedIt

Concerted campaigns in the Greater Mekong Subregion [GMS] to radically reduce the impact of malaria has lifted hopes a vital target to eradicate malaria from the region may be within reach.

Deyer Gobinath, a malaria technical officer with the World Health Organization (WHO) in Thailand, said the outlook is positive for eliminating severe forms of malaria across the region within the next decade.

The goal is for most of the GMS countries by 2025 to try and eliminate falciparium malaria – the most severe form of malaria – the falciparium malariia – and then by 2030 basically all forms or all species of malaria,” Gobinath said.

In 2015, WHO leaders said there were 14 million malaria cases across Southeast Asia, resulting in 26,000 deaths.  Globally, in the same year, the WHO reported 438,000 lives lost, mostly in Africa and warned that 3.2 billion people – almost half the world’s population – face health risks from the disease. 

Mortality rates decline; challenges remain

The campaigns in Southeast Asia cover Myanmar, Laos, Thailand, Cambodia and Vietnam, all reporting consistent declines in mortality rates, by as much as 49 percent since 2000.

Populations most vulnerable to the mosquito-borne disease are largely in remote border regions, isolated from infrastructure and immediate medical support.

The key areas of concern lie in regions between Thailand and Myanmar – also known as Burma – and in Cambodia among others.

But Saw Nay Htoo, director of the Burma Medical Association, said collaboration between medics and local communities has had a positive impact in reducing malaria’s impact.

“In the ground level we set up the malaria [clinic] post which we have at least one malaria health worker, according to the population they have, to detect malaria,” he said. “And if there is malaria positive then the patient is given the malaria medicine. So we have been doing this for three years. It seems our program is going very well – there are less malaria cases in the border areas.”

Combination of drugs

The fight against malaria is largely based on a combination of drugs known as Artemisinin-based Combination Therapy, or ACT, as the main line of drug treatment.

The World Health Organization’s Gobinath said Thailand’s medical infrastructure and funding support have all contributed to lowering the numbers of malaria cases.

“For malaria in Thailand here’s been quite a remarkable decrease – a steady decrease, decline in the number of confirmed cases of malaria. In the past 10 years or so something like 30,000 cases in 2012; to 2015 it was 19,000 to 20,000 cases. So it’s been a gradual but persistent decline of confirmed malaria cases,” he told VOA.

But he said for progress to be sustained it will require continued “political will and commitment.”

WHO officials said attention needs to focus on migrant worker populations moving across the region’s borders. Thai health authorities have taken steps to enable medical access to migrant populations at risk of malaria, largely in remote border areas.

The battle far from over

But challenges remain, said Maria Dorina Bustos, a WHO technical officer with responsibilities for monitoring drug resistant strains of malaria across 18 countries in the Asia Pacific.

Dorina Bustos said the region with drug resistant forms of malaria is spreading. “The Thai-Cambodia or the Thai-Myanmar border, you need to think about the Thai-Laos border because the Southern Laos drug resistance is also about evident – is documented, it is also there. And what is actually more alarming is happening in the Cambodia side,” she told VOA.

She said drug resistance becomes evident in the delay in clearance of the parasite from the patient. Dorina Bustos says the use of fake drugs and self-treatment also opens the way to drug resistance.

“What we are seeing in the last five years is that it is really emerging in the most parts of the region – initially just in the Western border of Cambodia and now it has also spread to the east and almost the whole country,” Dorina Bustos said.

She said there is a need for close monitoring of major population centers – especially in India and Africa – to ensure successful treatment and avoiding issues of the use of fake medicines.

A positive note has been ongoing investment and research in new drugs, including commitments by major pharmaceutical industries.

“It’s really here in the Mekong where we really have a problem. Cambodia, the borders of Thailand, the borders of Thai/Laos and Cambodia/Vietnam – it’s very specific in the Mekong region,” she said. “For Malaysia, the Philippines, Indonesia, Solomon Islands, Vanuatu and even India, Bangladesh and Nepal the ACT [Artemisinin-based Combination Therapy] is all working perfectly well.”
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From: MeNeedIt

Robert De Niro helped Burt Reynolds onto the red carpet for the Tribeca Film Festival premiere of his new movie “Dog Years” Saturday night in New York. It was a rare appearance for the 81-year old actor, who at times struggled to walk.

Reynolds was given a chair on the red carpet, so that he could speak to a limited number of press outlets about the film.

He was overjoyed at the turnout.

“Great to see Mr. De Niro, who I love, and … you know, all the people that I know,” Reynolds said. “It’s very sweet.”

In the film, which is still shopping for distribution, Reynolds portrays an aging movie star who realizes his best days are behind him. The actor sees similarities in the character with his own life.

Reynolds laughed at the obvious parallel with his own life, though he said, “I guess I’m doing all right. I think because it’s a hell of a turnout.”

Written and directed by Adam Rifkin, the film also stars “Modern Family’s” Ariel Winter, Chevy Chase and Nikki Blonsky.

Reynolds joked about working with younger co-stars.

“You don’t learn from young actors,” Reynolds said. “You just tell them how to behave.”
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From: MeNeedIt

This year marks the half-way point in an international campaign to provide children and adults the world over with access to life-saving vaccines. VOA’s Carol Pearson reports on the progress – and what’s at stake in this campaign.
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From: MeNeedIt

Six years ago, 194 countries signed on to the Global Vaccine Action Plan, an international campaign to provide children and adults around the world with access to life-saving vaccines.

The goal of the program is to prevent millions of people from getting vaccine-preventable diseases by the time it ends in 2020. The idea is to provide universal access to vaccines to protect people of all ages, from the very young to the very old.

Dr. Flavia Bustreo, is the assistant director-general for Family, Women’s and Children’s Health at the World Health Organization.

“Immunization and vaccines are the most powerful public health tools that we have currently, “ she said.

Millions of children saved

Bustreo says 35 years ago, 13 million children lost their lives from diseases that could be prevented by vaccines.

She says that number has been reduced to 6 million, but 6 million is still too high.

Today, 85 percent of children are vaccinated against measles and other deadly diseases, but Bustreo says more children need these vaccines.

“We need to have vaccination coverage that is about 90 percent, in order to have what we call the ‘herd effect’ … which means you cover the children who are vaccinated, but also, because of the reduction of transmission of infections, you also cover the children that are not vaccinated,” Bustreo said.

Final push on polio

Because of vaccines, polio is on the brink of eradication. Polio exists in two conflict zones: in northern Nigeria and along the border between Pakistan and Afghanistan. Last year there were 37 cases. Compare that to the 350,000 cases in 1988 when the eradication campaign began.

There’s a special urgency to vaccinate all children against polio. Dr. David Nabarro has worked on a number of health programs at the World Health Organization and now as a special envoy for the United Nations.

“The last part of eradicating any disease is always the hardest part,” he said. “If you don’t do it, you lose everything. To do it, you’ve got to really bring all the energy and commitment you can to bear, and it requires a special kind of dedication.”

Vaccines have prevented millions of deaths and countless numbers of children from becoming disabled. By 2020, at the conclusion of the Global Vaccine Action Plan, the U.N. wants to see countries strengthen routine immunizations for all children. It wants to complete the effort to end polio and to control other vaccine-preventable diseases. Also, the goal is to be well on the way in developing new vaccines for other diseases that plague our world.
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From: MeNeedIt

Earth Day is observed around the world with tree plantings, exhibits, cleanups and protests.
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From: MeNeedIt

Drawn-out deaths. Communities torn apart. Survivor’s guilt. Patrick Fallah says his memories of the days when the Ebola virus swept through Liberia are so awful that he sometimes has trouble focusing on the present.

“Sometimes when I have a flashback of the death of my son and others who died in the Ebola treatment unit, I don’t want to speak to people. I grieve so much that my mind is not really on what I am doing,” said Fallah, 30, who lost his 8-month-old son and stepmother and is president of the National Ebola Survivors Network of Liberia.

The trauma of the world’s deadliest Ebola outbreak, which killed more than 11,300, mostly in Liberia, Sierra Leone and Guinea, has left many survivors fighting a battle some worry will never end.

But Liberia, one of the world’s poorest countries and with just one psychiatrist, has announced the ambitious goal of expanding access to mental health care to 70 percent of its population in the next few years.

The World Health Organization declared an end to the Ebola outbreak in June, estimating that more than 10,000 people who had been infected have survived in the three West African countries, including more than 4,000 in Liberia.

As the world’s attention has turned to other crises, many Ebola survivors still face the psychological consequences of the epidemic, feeling guilt over their pasts and worry for their futures without resources to deal with the pain.

Mental health is often an expense far beyond the reach of impoverished countries. Liberia is still struggling to rebuild its basic health services after more than a decade of back-to-back civil wars that left a quarter-million people dead, with many killings carried out by drugged, under-age fighters notorious for hacking off survivors’ limbs.

Then Ebola arrived, frightening Liberians with its lack of a cure and its transmission through contact with body fluids. Many people became too scared to touch others or offer comfort as the death toll grew.

Now Liberia’s government has announced its ambition to expand mental health care access to its more than 4.2 million people, with help from the U.S.-based The Carter Center.

“After the civil war, people didn’t go through enough counseling. You have people already going through post-traumatic depression. Then Ebola came, and that built on what was already going on,” said Dr. Francis Kateh, Liberia’s deputy health minister and chief medical officer.

The Carter Center is helping to train Liberia’s health care workers to identify mental health issues.

Last month, 21 clinicians specializing in child and adolescent mental health graduated from the training. They join 187 mental health professionals who have been trained by the center since 2010 to work in prisons, with refugees or in other settings and are based in primary care clinics and hospitals around the country.

The Carter Center hopes to replicate its program in other countries, including Sierra Leone.

But educating the public will take time, the new mental health workers say.

“There are many people living with mental health problems in Liberia without knowing they are,” said one of the new specialists, Theophilus A. Joe.

Stigma remains around mental health issues, said Musulyn Massaqoui, a registered nurse and another recent graduate. Most people come to clinics only for physical issues, she said.

Ebola survivors often have hearing and vision problems, joint pain or chronic fatigue, according to the medical aid charity Doctors Without Borders. Many also are shunned by their communities and family members, making them vulnerable to mental health issues.

Children left orphaned by Ebola or who watched family members die are especially challenged, said Fallah with Liberia’s survivors’ network, which has about 1,800 members.

“They continue to have depression. They are still thinking about their parents,” he said. “Sometimes when they sit in the class, they don’t concentrate.” During the holidays, some feel so neglected that they “want to take up knife to kill themselves.”

Some of Liberia’s newly trained mental health workers have been placed in schools and orphanages to lessen the chances of stigma, said The Carter Center’s mental health program director, Eve Byrd.

That approach is critical, she said. “If you address childhood trauma early, you’re most likely to decrease symptoms of illness as the person ages.”

Stigma in Liberia has proven to be deadly. In March, an Ebola survivor who made the cover of Time magazine for her work as a nurse during the outbreak died when she experienced complications after childbirth and the nurses on duty were too afraid to touch her.

 
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From: MeNeedIt

European scientists are taking part in the March for Science demonstration taking place in hundreds of cities around the world to commemorate Earth Day. Science and research skeptics are becoming more mainstream in an era of populist and Eurosceptic movements. And on both sides of the Atlantic, there is less funding to support independent research.

Jean-Pascal van Ypersele, a professor at the University of Leuven, says shifting priorities in Europe has had an impact on the work of scientists.

“Now funds for fundamental research are much more difficult to get. Even if the budget remains the same or sometimes has increased, there was a shift in priorities towards research that is supposed to deliver more immediate results in terms of job creation or that kind of thing. Or research that helps the European industry to bring a product to the market. And climate scientists are not building any products that the European industries can sell.”

The European Union set a target for its member states that they should spend three percent of their budget on science, but many countries are only at around two percent.

Scientists hope that by joining forces globally, they will raise awareness about a global trend that seems to take science less serious. With U.S. President Donald Trump in the White House and populist and Eurosceptic movements gaining popularity in Europe, scientists say their budgets are being reduced and their work is being taken less serious.

Bas Eickhout, a scientist and member of the European Parliament for the Greens Party, says climate change policy should not be seen as a “left wing hobby.” He calls on scientist to be more involved in the decision making process.

“Not in policy making itself but providing information to politicians is crucial. And quite often once we start with decision making, that information is just lost. Scientist are really a bit too scared for the word lobby, and I don’t think its lobbying that your doing, but its also trying to feed decision making also during the negotiations, and not only at the beginning.”

The March for Science is a volunteer based movement and organizers say there is an “alarming trend toward discrediting scientific consensus and restricting scientific discovery.” The organizers aim to celebrate science and hold political and science leaders accountable, but do not affiliate with any political party.

Sofie Vanthournout, director of Sense about Science EU, a charity advocating the importance of science, says the march aims to change the perspective of citizens and politicians who doubt the importance of science:

“The message that we want to bring it is important for every aspect of our lives, for every aspect of society. Whether it’s in technology that we use in our daily lives or whether it is for important decisions that politicians make about our lives. We don’t want scientists to tell politicians what to do but we need the politicians to have access to all of the facts and all of the knowledge that is available.”

One week after the March of Science, the Peoples Climate March will follow. In 2015, the world came together to sign the Paris Accord, an agreement signed by almost all nations in the world to curb global warming.

U.S. President Trump promised during his election campaign to pull the United States out of the international accord, but later softened his stance, saying he thinks there is “some connectivity” between human activity and global warming.

 
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From: MeNeedIt

Scientists on Saturday took the unprecedented step of staging marches in more than 600 cities worldwide in the face of what they see as a growing political assault on evidence-based knowledge.

Thousands of scientists and their supporters attended March for Science events in such cities as  Cape Town, London, Madrid and Seoul, as well as in Australia, Brazil, Canada and Nigeria.

In Berlin, organizers said about 10,000 people marched toward the Brandenberg Gate holding up placards that read “Facts not feelings” and “We love experts — those with evidence.”

Marchers in Geneva carried signs that said “Science — A Candle in the Dark” and “Science is the Answer.”

In London, demonstrators marched from the Science Museum to Parliament Square in Westminster holding placards supporting science.

New role for scientists

The March for Science thrusted scientists, who generally avoid advocacy and whose work is based on impartial experimentation, into a more visible spotlight.

For nuclear physics graduate student Chelsea Bartram, White House adviser Kellyanne Conway’s “alternative facts” were the last straw.

President Donald Trump had disputed photographic evidence of the size of his inauguration crowd. Reporters challenged him, prompting Conway to respond that the administration had given “alternative facts.”

“Many scientists I know, myself included, spend so many hours in the lab sacrificing enormous amounts of their life for this abstract idea” that understanding reality can benefit human civilization, said Bartram, who is pursuing a doctorate at the University of North Carolina at Chapel Hill.

“And then to have someone say, ‘Well, that’s not important anymore,’ it’s so devastating,” Bartram added.

So Bartram planned to support science’s role in government decisions on health, safety, the economy and more by joining demonstrators at the flagship March for Science event in Washington.

Karen Tanyer, an English teacher, and her son, Michael, 10, traveled to Washington from Efro, New Jersey, to participate in the march because “science affects everything.”

“When we look at art today, it is all influenced by science and the properties of science that we’ve exploited to express the human spirit,” Karen Tanyer told VOA.

The Washington event featured speakers and several large teach-in tents on the National Mall where scientists, educators and leaders from a variety of disciplines discussed their work, effective science communication strategies and training in public advocacy. Organizers said the event was nonpartisan and was not aimed against the Trump administration or any politician or party.

Proposed cuts to programs

Nevertheless, the March for Science was effectively a protest against steep cuts Trump has proposed for federal science and research budgets and his administration’s skepticism about climate change.

The international event coincided with Earth Day, which Trump recognized by issuing a statement saying his administration was committed to supporting science and protecting the environment.

“Rigorous science is critical to my administration’s efforts to achieve the twin goals of economic growth and environmental protection,” the statement said.

Organizers of the March for Science said it was the first step in a global movement to acknowledge and defend the vital role science plays in everyday life.

“Science extends our lives, protects our planet, puts food on our table [and] contributes to the economy,” said Caroline Weinberg, national co-chair of the March for Science.

“Policymakers threaten our present and future by ignoring scientific evidence when crafting policy, threatening scientific advancement through budget cuts and limiting the public’s knowledge by silencing scientists,” Weinberg said.

Dr. Mona Hanna-Attisha, a first-generation Iraqi immigrant, is the pediatrician who alerted officials in Flint, Michigan, that the city’s water had been contaminated with lead. She was a March for Science honorary national co-chair.

“We march for science so that scientists have the freedom, like I did, to speak out, free from politicization and to continue to make the world a better place,” Hanna-Attisha said.

Tipping point

Organizers had not released crowd size estimates by Saturday afternoon. But the dispute over crowd sizes was just one small example of what scientists see as a larger pattern.

During the U.S. presidential campaign, Trump dismissed the scientific consensus about the dangers of human-induced climate change. His appointee to lead the Environmental Protection Agency, Scott Pruitt, also does not accept climate science. He has repeatedly clashed with the agency he now heads.

But scientists say their frustration has been building for decades.

“We might have reached a tipping point now, but acting as though this is a new thing is giving too much credit to the current administration,” national co-chair Weinberg said.

And it goes far beyond climate change, Weinberg added. “It’s about not paying attention to the best research on things like food stamps. It’s about cutting things like Head Start and after-school programs,” to name a few, she said. “And that all affects health, because that’s a time to set kids on the right path.”

Critics said a public protest risked further politicizing science, turning scientists into just another interest group.

Bartram summed up a widespread response: On hot-button issues such as climate change, opponents have already done it. “I don’t think anything we do is going to further politicize it,” Weinberg said.

Disconnect

But if the goal is to get policymakers to listen, “a march isn’t going to change anything,” said Rob Young, head of coastal research at Western Carolina University in Cullowhee, North Carolina.

Young said much of the problem stems from the growing disconnect between scientists and voters, especially the rural and working-class people who voted for Trump.

Scientists need to get out of the lab more, he said, and explain how their work affects people’s health and livelihoods.

That’s what march organizers said they hoped for, too.

Geochemist Eric Davidson, president of the 60,000-member American Geophysical Union, one of the march co-sponsors, said a major post-march goal is  more public engagement.

“I think the day is gone when scientists can stay in their ivory towers and assume that everyone is going to recognize their value,” Davidson added.
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From: MeNeedIt

Ear infections are one of those things almost everyone has to deal with. They’re painful, but generally easily treatable. But for many people, chronic ear infections can significantly affect their hearing and their quality of life. Polish doctors may have discovered a tiny solution for what can be a big problem. VOA’s Kevin Enochs reports.
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From: MeNeedIt

The co-founder of Microsoft, billionaire philanthropist Bill Gates, has given a passionate defense of foreign aid and voiced fears that the political climate in the US and Britain could see aid budgets cut. In a speech in London this week, he warned that withdrawing aid would create a ‘leadership vacuum that others will fill.’ Henry Ridgwell reports.
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From: MeNeedIt