Security Issues Constrain DR Congo Ebola Operation

The World Health Organization says security issues could hamper efforts to contain an Ebola outbreak in the eastern Democratic Republic of Congo. The outbreak is in conflict-ridden North Kivu province, where some areas are too dangerous for health care workers to go.

As of Wednesday, about two weeks after the Ebola outbreak was declared in North Kivu province, there were 78 confirmed and probable cases of the viral disease, including 44 deaths.

That is nearly double the number of cases reported during a recent and separate Ebola outbreak in Equateur Province.

Health workers have fanned out in North Kivu, tracking down contacts of Ebola victims and giving them an experimental vaccine. But WHO spokesman Tarik Jasarevic says more cases of Ebola are expected to be seen in the coming days and weeks.

“It will get worse before it gets better,” he said. “We do not know if we are having all transmission chains identified. We expect to see more cases as a result of earlier infections and these infections are developing into illness.”

He tells VOA that health workers are able to move around freely in the towns of Mangina and Beni, which are the epicenters of the disease. It is the other parts of the province that have the WHO worried.

“There are areas just next to Mangina that are level four on the UNDSS Security scale, which means that it is an area not to go to … We still do not have a full epidemiological picture, so … the worst-case scenario is that we have these security blind spots where the epidemic could take hold and then we do not know about it,” he said.

The WHO reports it is using the same Ebola vaccine that helped contain the outbreak in Equateur province.

So far, it says nearly 500 people in North Kivu have been vaccinated, including health care workers and people who have come in contact with confirmed cases of the deadly disease.

From: MeNeedIt

Security Issues Constrain DR Congo Ebola Operation

The World Health Organization says security issues could hamper efforts to contain an Ebola outbreak in the eastern Democratic Republic of Congo. The outbreak is in conflict-ridden North Kivu province, where some areas are too dangerous for health care workers to go.

As of Wednesday, about two weeks after the Ebola outbreak was declared in North Kivu province, there were 78 confirmed and probable cases of the viral disease, including 44 deaths.

That is nearly double the number of cases reported during a recent and separate Ebola outbreak in Equateur Province.

Health workers have fanned out in North Kivu, tracking down contacts of Ebola victims and giving them an experimental vaccine. But WHO spokesman Tarik Jasarevic says more cases of Ebola are expected to be seen in the coming days and weeks.

“It will get worse before it gets better,” he said. “We do not know if we are having all transmission chains identified. We expect to see more cases as a result of earlier infections and these infections are developing into illness.”

He tells VOA that health workers are able to move around freely in the towns of Mangina and Beni, which are the epicenters of the disease. It is the other parts of the province that have the WHO worried.

“There are areas just next to Mangina that are level four on the UNDSS Security scale, which means that it is an area not to go to … We still do not have a full epidemiological picture, so … the worst-case scenario is that we have these security blind spots where the epidemic could take hold and then we do not know about it,” he said.

The WHO reports it is using the same Ebola vaccine that helped contain the outbreak in Equateur province.

So far, it says nearly 500 people in North Kivu have been vaccinated, including health care workers and people who have come in contact with confirmed cases of the deadly disease.

From: MeNeedIt

Google Workers Protest China Plan Secrecy

Google is planning a return to China.

But the project is shrouded in secrecy, and employees are demanding transparency.

According to a report by The New York Times on Thursday, August 16, a petition calling for more oversight and accountability in the project racked up more than 1,000 signatures.

Reuters reported this month, the app is a bid to win approval from Beijing to provide a mobile search engine in China.

However, employees are concerned the app would support China’s restrictions on free expression and ultimately violate the company’s ‘don’t be evil’ code of conduct.

The petition, seen by Reuters says, “We urgently need more transparency, a seat at the table and a commitment to clear and open processes: Google employees need to know what we’re building.”

The company declined to comment.

Sources say the project – codenamed Dragonfly – would block certain websites and search terms.

It would also stand in stark contrast to eight years ago, when Google left China in protest of Beijing’s censorship.

Company executives have not commented publicly on Dragonfly.

But in a transcript seen by Reuters, Google’s Chief Executive Sundar Pichai told employees “it’s all very unclear” whether Google would return to China at all.

He also said that development is still in the early stages, and that sharing information too early could quote “cause issues”.

From: MeNeedIt

Google Workers Protest China Plan Secrecy

Google is planning a return to China.

But the project is shrouded in secrecy, and employees are demanding transparency.

According to a report by The New York Times on Thursday, August 16, a petition calling for more oversight and accountability in the project racked up more than 1,000 signatures.

Reuters reported this month, the app is a bid to win approval from Beijing to provide a mobile search engine in China.

However, employees are concerned the app would support China’s restrictions on free expression and ultimately violate the company’s ‘don’t be evil’ code of conduct.

The petition, seen by Reuters says, “We urgently need more transparency, a seat at the table and a commitment to clear and open processes: Google employees need to know what we’re building.”

The company declined to comment.

Sources say the project – codenamed Dragonfly – would block certain websites and search terms.

It would also stand in stark contrast to eight years ago, when Google left China in protest of Beijing’s censorship.

Company executives have not commented publicly on Dragonfly.

But in a transcript seen by Reuters, Google’s Chief Executive Sundar Pichai told employees “it’s all very unclear” whether Google would return to China at all.

He also said that development is still in the early stages, and that sharing information too early could quote “cause issues”.

From: MeNeedIt

Google Workers Protest China Plan Secrecy

Google is planning a return to China.

But the project is shrouded in secrecy, and employees are demanding transparency.

According to a report by The New York Times on Thursday, August 16, a petition calling for more oversight and accountability in the project racked up more than 1,000 signatures.

Reuters reported this month, the app is a bid to win approval from Beijing to provide a mobile search engine in China.

However, employees are concerned the app would support China’s restrictions on free expression and ultimately violate the company’s ‘don’t be evil’ code of conduct.

The petition, seen by Reuters says, “We urgently need more transparency, a seat at the table and a commitment to clear and open processes: Google employees need to know what we’re building.”

The company declined to comment.

Sources say the project – codenamed Dragonfly – would block certain websites and search terms.

It would also stand in stark contrast to eight years ago, when Google left China in protest of Beijing’s censorship.

Company executives have not commented publicly on Dragonfly.

But in a transcript seen by Reuters, Google’s Chief Executive Sundar Pichai told employees “it’s all very unclear” whether Google would return to China at all.

He also said that development is still in the early stages, and that sharing information too early could quote “cause issues”.

From: MeNeedIt

Google Workers Protest China Plan Secrecy

Google is planning a return to China.

But the project is shrouded in secrecy, and employees are demanding transparency.

According to a report by The New York Times on Thursday, August 16, a petition calling for more oversight and accountability in the project racked up more than 1,000 signatures.

Reuters reported this month, the app is a bid to win approval from Beijing to provide a mobile search engine in China.

However, employees are concerned the app would support China’s restrictions on free expression and ultimately violate the company’s ‘don’t be evil’ code of conduct.

The petition, seen by Reuters says, “We urgently need more transparency, a seat at the table and a commitment to clear and open processes: Google employees need to know what we’re building.”

The company declined to comment.

Sources say the project – codenamed Dragonfly – would block certain websites and search terms.

It would also stand in stark contrast to eight years ago, when Google left China in protest of Beijing’s censorship.

Company executives have not commented publicly on Dragonfly.

But in a transcript seen by Reuters, Google’s Chief Executive Sundar Pichai told employees “it’s all very unclear” whether Google would return to China at all.

He also said that development is still in the early stages, and that sharing information too early could quote “cause issues”.

From: MeNeedIt

Franklin Leaves a Powerful Civil Rights Legacy

Aretha Franklin, who was born and rose to fame during the segregation era and went on to sing at the inauguration of the first black president, often used her talent, fortune and platform to inspire millions of black Americans and support the fight for racial equality.

“She not only provided the soundtrack for the civil rights movement, Aretha’s music transcended race, nationality and religion and helped people from all backgrounds to recognize what they had in common,” said longtime civil rights leader the Rev. Joseph E. Lowery.

Franklin, who died Thursday at 76, was a close confidante of the Rev. Martin Luther King Jr. and a financial lifeline to the civil rights organization he co-founded, the Southern Christian Leadership Conference.

​Father’s commitment

The Queen of Soul’s commitment to civil rights was instilled by her father, the Rev. C.L. Franklin, who also knew King and preached social justice from his pulpit at New Bethel Baptist Church in Detroit.

The church, in fact, was the first place King gave his “I Have a Dream” speech in 1963. Among those in the congregation were Aretha Franklin and Mahalia Jackson. It was Jackson who later urged the civil rights leader to “tell them about the dream, Martin” at the March on Washington, where he delivered the oration for which he is most famous.

Franklin recorded “Respect” on Valentine’s Day 1967. Black Americans had won federal legislation outlawing segregation and protecting their voting rights, particularly in the Deep South.

But blacks were still a year away from the Fair Housing Act. And just months after the song was recorded, urban centers, including Franklin’s hometown of Detroit, would burn, exposing police brutality and unequal living conditions and job opportunities.

Financial backer

“Her songs were songs of the movement,” Andrew Young, the former King lieutenant and U.N. ambassador, said Thursday. “R-E-S-P-E-C-T. … That’s basically what we wanted. The movement was about respect.”

The SCLC often struggled financially, but Franklin played a vital role in keeping the movement afloat.

“Almost every time we needed money, there were two people we could always count on: Aretha Franklin and Harry Belafonte,” Young said. “They would get together and have a concert, and that would put us back on our feet.”

Strong faith

King and Franklin were like spiritual siblings, sharing a bond rooted in their Christian faith, Young said. King would often ask Franklin to sing his favorite songs, “Amazing Grace” or “Precious Lord, Take My Hand.” When King was assassinated in 1968, Franklin sang “Precious Lord” at his funeral in Atlanta.

Franklin’s “Amazing Grace” was also a comfort to the Rev. Al Sharpton when he was a boy. He recalled that his mother would play the song nonstop in their Brooklyn home after his father left.

As an adult and an activist, Sharpton became friends with the soul singer. He noted her unwavering faith, which she brought with her on stage to every performance.

“Whether it was the White House, Radio City Music Hall or the Apollo Theater, she always did gospel numbers,” Sharpton said. “She was unapologetically a hardcore, faith-believing Baptist. At the height of her career, she cut a gospel album. Who does that? Her faith is what motivated her.”

Committed to social justice

Long after the civil rights movement ended, Franklin remained committed to social justice, helping Sharpton as he began his organization, the National Action Network, in New York. She would call Sharpton for updates on the emerging Black Lives Matter movement, asking about such cases as those of Trayvon Martin and Eric Garner.

“She gave so much to so many people, from Dr. King, to Mandela, to Barack Obama,” said Rev. Jesse Jackson, a longtime friend who visited her the day before her death.

Her presence and influence were as valuable to the movement as her financial contributions, Sharpton said.

“To have someone like that that involved and interested … was a statement,” he said. “It gave all the credibility in the world. Others had celebrity, but she had gravity and respect.”

From: MeNeedIt

Franklin Leaves a Powerful Civil Rights Legacy

Aretha Franklin, who was born and rose to fame during the segregation era and went on to sing at the inauguration of the first black president, often used her talent, fortune and platform to inspire millions of black Americans and support the fight for racial equality.

“She not only provided the soundtrack for the civil rights movement, Aretha’s music transcended race, nationality and religion and helped people from all backgrounds to recognize what they had in common,” said longtime civil rights leader the Rev. Joseph E. Lowery.

Franklin, who died Thursday at 76, was a close confidante of the Rev. Martin Luther King Jr. and a financial lifeline to the civil rights organization he co-founded, the Southern Christian Leadership Conference.

​Father’s commitment

The Queen of Soul’s commitment to civil rights was instilled by her father, the Rev. C.L. Franklin, who also knew King and preached social justice from his pulpit at New Bethel Baptist Church in Detroit.

The church, in fact, was the first place King gave his “I Have a Dream” speech in 1963. Among those in the congregation were Aretha Franklin and Mahalia Jackson. It was Jackson who later urged the civil rights leader to “tell them about the dream, Martin” at the March on Washington, where he delivered the oration for which he is most famous.

Franklin recorded “Respect” on Valentine’s Day 1967. Black Americans had won federal legislation outlawing segregation and protecting their voting rights, particularly in the Deep South.

But blacks were still a year away from the Fair Housing Act. And just months after the song was recorded, urban centers, including Franklin’s hometown of Detroit, would burn, exposing police brutality and unequal living conditions and job opportunities.

Financial backer

“Her songs were songs of the movement,” Andrew Young, the former King lieutenant and U.N. ambassador, said Thursday. “R-E-S-P-E-C-T. … That’s basically what we wanted. The movement was about respect.”

The SCLC often struggled financially, but Franklin played a vital role in keeping the movement afloat.

“Almost every time we needed money, there were two people we could always count on: Aretha Franklin and Harry Belafonte,” Young said. “They would get together and have a concert, and that would put us back on our feet.”

Strong faith

King and Franklin were like spiritual siblings, sharing a bond rooted in their Christian faith, Young said. King would often ask Franklin to sing his favorite songs, “Amazing Grace” or “Precious Lord, Take My Hand.” When King was assassinated in 1968, Franklin sang “Precious Lord” at his funeral in Atlanta.

Franklin’s “Amazing Grace” was also a comfort to the Rev. Al Sharpton when he was a boy. He recalled that his mother would play the song nonstop in their Brooklyn home after his father left.

As an adult and an activist, Sharpton became friends with the soul singer. He noted her unwavering faith, which she brought with her on stage to every performance.

“Whether it was the White House, Radio City Music Hall or the Apollo Theater, she always did gospel numbers,” Sharpton said. “She was unapologetically a hardcore, faith-believing Baptist. At the height of her career, she cut a gospel album. Who does that? Her faith is what motivated her.”

Committed to social justice

Long after the civil rights movement ended, Franklin remained committed to social justice, helping Sharpton as he began his organization, the National Action Network, in New York. She would call Sharpton for updates on the emerging Black Lives Matter movement, asking about such cases as those of Trayvon Martin and Eric Garner.

“She gave so much to so many people, from Dr. King, to Mandela, to Barack Obama,” said Rev. Jesse Jackson, a longtime friend who visited her the day before her death.

Her presence and influence were as valuable to the movement as her financial contributions, Sharpton said.

“To have someone like that that involved and interested … was a statement,” he said. “It gave all the credibility in the world. Others had celebrity, but she had gravity and respect.”

From: MeNeedIt

Antibodies Could Knock Out Ebola Virus

In 1995, a patient sick with the Ebola virus, in what was then called Zaire and is now the Democratic Republic of the Congo, miraculously recovered from this deadly disease. At that time, when the virus first jumped from animals to man, Ebola meant almost certain death.

Doctors found that this patient had antibodies to fight the virus in his bloodstream even after he recovered. 

Dr. Anthony Fauci, head of the National Institute of Allergy and Infectious Diseases at the National Institutes of Health, invited the patient to the U.S., where researchers cloned the cell that had helped him beat Ebola.

“We brought the person back to the United States to draw his blood and try to clone the B cells that make the antibodies that this person had produced … to then, essentially, clear his virus and, hopefully, protect him against any future exposure,” Fauci told VOA. 

Because the NIH scientists made numerous copies of that cell, it is called a monoclonal antibody — in this case, mAB114. It’s hoped that it can be used to target the Zaire strain of Ebola currently spreading in eastern Congo.

Fauci said mAB114 is still experimental.

“We have done a number of tests in an animal model and have shown that when you infect an animal up to five days after they become infected, and you passively transfer this antibody, you can actually protect the animals from getting sick and they recover,” he said.

Not all treatments that work in animals work in humans, something Fauci knows all too well. One treatment for HIV/AIDS that Fauci found worked well in monkeys had disastrous effects when tested in humans.

Fauci’s staff is conducting a phase one clinical trial in volunteers at the NIH hospital to make sure mAB114 is safe. So far, no one can say whether the treatment works, but because of the dire situation in Congo, and the fear the virus will spread in the armed conflict that is going on in the region, Fauci said the antibody has been given to five people with Ebola.

At a news conference Tuesday, Dr. Tedros Adhanom Ghebreyesus, director-general of the World Health Organization, said he had been told they were doing well.

As of now, there’s no approved treatment for the disease, although there is a vaccine that protects people who may have been exposed to the virus but who are not sick. 

Other experimental treatments are also being used to help end the outbreak in Congo. One of them is ZMapp, a combination of three monoclonal antibodies. In 2016, NIH found ZMapp safe and well-tolerated, but without an outbreak, it is impossible to prove effectiveness. 

Fauci said another antiviral drug, remdesivir, is being used in patients with Ebola from West Africa, even though that outbreak is over. Scientists have found the Ebola virus can remain in the semen, so men are being treated to prevent further spread.

Remdesivir, or GS-5734, is produced by Gilead. On its website, Gilead says remdesivir is thought to work by blocking a key enzyme the virus needs to reproduce itself. Tomas Cihlar, Gilead’s vice president for biology, is quoted as saying, “Based on animal studies, we believe that the compound is able to penetrate the organs and tissues throughout the body where Ebola replicates.”

So far, there are no proven treatments for Ebola. Scientists are hopeful that that therapeutic antibodies could be the best way to stop this virus. An international study led by Scripps Research suggests that antibodies may be valuable treatments against new viruses and could help a patient’s immune system fight the Ebola virus after being infected.

From: MeNeedIt

Antibodies Could Knock Out Ebola Virus

In 1995, a patient sick with the Ebola virus, in what was then called Zaire and is now the Democratic Republic of the Congo, miraculously recovered from this deadly disease. At that time, when the virus first jumped from animals to man, Ebola meant almost certain death.

Doctors found that this patient had antibodies to fight the virus in his bloodstream even after he recovered. 

Dr. Anthony Fauci, head of the National Institute of Allergy and Infectious Diseases at the National Institutes of Health, invited the patient to the U.S., where researchers cloned the cell that had helped him beat Ebola.

“We brought the person back to the United States to draw his blood and try to clone the B cells that make the antibodies that this person had produced … to then, essentially, clear his virus and, hopefully, protect him against any future exposure,” Fauci told VOA. 

Because the NIH scientists made numerous copies of that cell, it is called a monoclonal antibody — in this case, mAB114. It’s hoped that it can be used to target the Zaire strain of Ebola currently spreading in eastern Congo.

Fauci said mAB114 is still experimental.

“We have done a number of tests in an animal model and have shown that when you infect an animal up to five days after they become infected, and you passively transfer this antibody, you can actually protect the animals from getting sick and they recover,” he said.

Not all treatments that work in animals work in humans, something Fauci knows all too well. One treatment for HIV/AIDS that Fauci found worked well in monkeys had disastrous effects when tested in humans.

Fauci’s staff is conducting a phase one clinical trial in volunteers at the NIH hospital to make sure mAB114 is safe. So far, no one can say whether the treatment works, but because of the dire situation in Congo, and the fear the virus will spread in the armed conflict that is going on in the region, Fauci said the antibody has been given to five people with Ebola.

At a news conference Tuesday, Dr. Tedros Adhanom Ghebreyesus, director-general of the World Health Organization, said he had been told they were doing well.

As of now, there’s no approved treatment for the disease, although there is a vaccine that protects people who may have been exposed to the virus but who are not sick. 

Other experimental treatments are also being used to help end the outbreak in Congo. One of them is ZMapp, a combination of three monoclonal antibodies. In 2016, NIH found ZMapp safe and well-tolerated, but without an outbreak, it is impossible to prove effectiveness. 

Fauci said another antiviral drug, remdesivir, is being used in patients with Ebola from West Africa, even though that outbreak is over. Scientists have found the Ebola virus can remain in the semen, so men are being treated to prevent further spread.

Remdesivir, or GS-5734, is produced by Gilead. On its website, Gilead says remdesivir is thought to work by blocking a key enzyme the virus needs to reproduce itself. Tomas Cihlar, Gilead’s vice president for biology, is quoted as saying, “Based on animal studies, we believe that the compound is able to penetrate the organs and tissues throughout the body where Ebola replicates.”

So far, there are no proven treatments for Ebola. Scientists are hopeful that that therapeutic antibodies could be the best way to stop this virus. An international study led by Scripps Research suggests that antibodies may be valuable treatments against new viruses and could help a patient’s immune system fight the Ebola virus after being infected.

From: MeNeedIt

Emma Thompson, 59, Wants More Film Roles for Older Women

Oscar-winning British actress Emma Thompson, now starring at age 59 as a family court judge in the dramatic movie “The Children Act,” said on Thursday that older women still need more opportunity on the big screen.

Known for period dramas such as “Howards End” and “Sense and Sensibility,” Thompson plays a judge who struggles with a legal decision while also dealing with trouble in her marriage.

At the movie’s red-carpet premiere, Thompson said she was drawn to the role of a woman who has gained power in “a very male bastion.”

“I’d never seen a story about a female judge, and I think in our patriarchal world, when you hear the word judge, you automatically think, ‘Oh, it’s a man,’” Thompson said.

She also said the lack of good film roles for older women remains a long-running problem.

“Men don’t have any problem with that,” Thompson said. “It’s something that hasn’t yet properly changed.

“We are seeing some really good and interesting new roles, so one’s got to be hopeful,” she added.

From: MeNeedIt