There’s an exciting new breakthrough in treating deadly brain tumors. Doctors have used a modified polio virus to treat people with brain cancer. VOA’s Carol Pearson reports the results, so far, are promising.
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From: MeNeedIt
Advertising and marketing. Advertising is the practice and techniques employed to bring attention to a product or service. Advertising aims to put a product or service in the spotlight in hopes of drawing it attention from consumers
Enslaved on a Thai fishing vessel for 11 years, Tun Lin saw his fellow workers lose their minds one after another, with one fisherman jumping into the sea to end his
life.
Some would start murmuring or laughing to themselves as they worked day and night in Indonesian waters on the cramped boat, often surviving on fish they caught and drinking water leaking from an onboard freezer.
“It was like a floating prison – actually, worse than prison,” the Burmese fisherman, who was sold into slavery, told the Thomson Reuters Foundation in Samut Sakhon, a Thai fishing hub some 40 km (25 miles) southwest of the capital Bangkok.
The 36-year-old, who was rescued in 2015 after losing four fingers and being stranded on a remote island for years without pay, is now lobbying for fishermen’s rights with the Thai and Migrant Fishers Union Group (TMFG).
Under growing consumer pressure, Thailand has introduced a raft of modern technologies since 2015 – from satellites to optical scanning and electronic payment services – to crack down on abuses in its multibillion-dollar fishing industry.
It is one of a growing number of countries using innovation to deal with modern slavery, from mobile apps in India to blockchain in Moldova, but experts warn against over-reliance on tech as a silver bullet without stronger workers’ rights.
“Technology can be a double-edged sword,” said Patima Tungpuchayakul, co-founder of the Labor Rights Promotion Network Foundation, a Thai advocacy group. “It has become an excuse the government is using to justify they have done something, but in practice they don’t use it to solve the problem.”
More than half the estimated 600,000 industry workers are migrants, often from poor neighboring countries such as Cambodia and Myanmar, United Nations (U.N.) data shows.
Tracking Devices
After the European Union threatened to ban fish exports from Thailand, and the U.S. State Department said it was failing to tackle human trafficking, the Southeast Asian country toughened up its laws and increased fines for violations.
It banned the use of workers aged below 18 and ordered fishermen to be given contracts and be paid through electronic bank transfers.
Authorities ordered Thai vessels operating outside national waters to have satellite communications for workers to contact their families or report problems at sea, plus tracking devices to spot illegal fishing.
“We are serious in law enforcement regarding human trafficking and illegal labor cases,” said Weerachon Sukhontapatipak, a Thai government spokesman. “There might not be abrupt change … it will take time.”
Thailand is also rolling out an ambitious plan, using iris, facial and fingerprint scans to record fishermen’s identities to make sure they are on the boats they are registered with and help inspectors spot trafficking victims.
Rights groups meanwhile have tried to use satellites to pinpoint the location of ships that remain at sea for long periods, potentially indicating enslavement.
But human trafficking expert Benjamin Smith said using satellites to tackle slavery at sea was not easy unless there is a lead on where to track in the vast ocean.
“I think people underestimate the size of the ocean and the ability to pinpoint where something as small as a boat is,” Smith from the U.N. Office on Drugs and Crime (UNODC) said. “If you have good information, intelligence, then satellite images can be good … It has to be a small part of a much bigger effort.”
Smith also highlighted difficulties prosecuting cross-border trafficking cases and maritime police funding shortages, adding that continued consumer pressure on firms to clean up their supply chains could be a potent force to help end slavery.
“That’s probably the best way you can start,” he said.
Good News
Fishermen remain at risk of forced labor and the wages of some continue to be withheld, the International Labor Organization (ILO) said in March.
To combat slavery, firms must improve workers’ lives, rather than cutting labor costs and recruiting informally to meet demand for cheaper goods, experts say.
“Smaller owners are getting squeezed, and still rely on brokers and agents, who dupe workers and keep them ignorant of their rights and conditions on the boat,” said Sunai Phasuk, a researcher with lobby group Human Rights Watch in Bangkok.
Workers are set to become more vocal with the May launch of the Fishers’ Rights Network, which aims to combat abuses, backed by the world’s largest canned tuna producer, Thai Union, and the International Transport Workers’ Federation (ITF).
“Without enforceable rights at the workplace and the strength that comes from being represented by a union, labor rights violations and the mistreatment will continue,” said Johnny Hansen, chairman of ITF’s fisheries section.
Thailand’s ratification this month of the ILO protocol on forced labor also offers hope. It is the first Asian country to promise to combat all forms of the crime, including trafficking, and to protect and compensate victims.
“We have … committed to changing the law to allow workers to form unions, so we can work together to solve the problems,” said Thanaporn Sriyakul, an advisor to the deputy prime minister. “But the process is long, and it will take time.”
Thailand has also pledged to ratify two other conventions on collective bargaining and the right to organize, which campaigners say would better protect seafood workers.
This would be good news for Lin’s fishermen’s group, which has helped rescue more than 60 people since 2015, but has no legal status as Thai law does not permit fisher unions, leading rights advocates to use other terms, like workers’ groups.
“There are still lots of victims, and I want to help them,” Lin said. “As fishermen who have suffered in a similar manner, we understand each other’s needs and are able to help better.”
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From: MeNeedIt
A Japanese space explorer arrived at an asteroid Wednesday after a 3 1/2-year journey and now begins its real work of trying to blow a crater to collect samples to eventually bring back to Earth.
The unmanned Hayabusa2 spacecraft reached its base of operations about 20 kilometers (12 miles) from the asteroid and some 280 million kilometers (170 million miles) from Earth, the Japan Space Exploration Agency said.
Over the next year and a half, the spacecraft will attempt three brief touch-and-go landings to collect samples. If the retrieval and the return journey are successful, the asteroid material could provide clues to the origin of the solar system and life on Earth.
The mission is challenging. The robotic explorer will spend about two months looking for suitable landing places on the uneven surface. Because of the high surface temperature, it will stay for only a few seconds each time it lands.
The asteroid, named Ryugu after an undersea palace in a Japanese folktale, is about 900 meters (3,000 feet) in diameter. In photos released by JAXA, the Japanese space agency, it appears more cube-shaped than round. A number of large craters can be seen, which Project Manager Yuichi Tsuda said in an online post makes the selection of landing points “both interesting and difficult.”
The first touchdown is planned for September or October. Before the final touchdown scheduled for April-May, Hayabusa2 will send out a squat cylinder that will detonate above the asteroid, shooting a 2-kilogram (4.4-pound) copper projectile into it at high speed to make a crater.
Hayabusa2 will hide on the other side of the asteroid to protect itself during the operation and wait another two to three weeks to make sure any debris that could damage the explorer has cleared. It will then attempt to land at or near the crater to collect underground material that was blown out of the crater, in addition to the surface material from the earlier touchdowns.
The spacecraft will also deploy three rovers that don’t have wheels but can hop around on the surface of the asteroid to conduct probes. Hayabusa2 will also send a French-German-made lander to study the surface with four observation devices.
Asteroids, which orbit the sun but are much smaller than planets, are among the oldest objects in the solar system. As such, they may help explain how Earth evolved, including the formation of oceans and the start of life.
Hayabusa2 was launched in December 2014 and is due to return to Earth at the end of 2020. An earlier Hayabusa mission from 2003 to 2010 collected samples from a different type of asteroid and took three years longer than planned after a series of technical glitches, including a fuel leak and a loss of contact for seven weeks.
NASA also has an ongoing asteroid mission. Its Osiris-Rex spacecraft is expected to reach the asteroid Bennu later this year and return with samples in 2023.
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From: MeNeedIt
Warming waters have reduced the harvest of Alaska’s prized Copper River salmon to just a small fraction of last year’s harvest, Alaska biologists say.
The runs of Copper River salmon were so low that the Alaska Department of Fish and Game shut down the commercial harvest last month, halting what is usually a three-month season after less than two weeks. Earlier this month, the department also shut down most of the harvest that residents along the river conduct to feed their families.
The total commercial harvest for Alaska’s marquee Copper River salmon this year after it was halted at the end of May was about 32,000 fish, the Alaska Department of Fish and Game reported. That compares with the department’s pre-season forecast of over 1.2 million and an average annual harvest of over 1.4 million fish in the prior decade.
State biologists blame warming in the Gulf of Alaska for the diminished run of Copper River salmon, prized for its rich flavor, high oil content and deep-red color.
The fish spend most of their lives in the ocean, and those waters were 3 to 5 degrees Celsius (5 to 9 degrees Fahrenheit) warmer than normal, thanks to a warm and persistent North Pacific water mass that climate scientists have dubbed “the Blob,” along with other factors, said Mark Somerville, a biologist with the Alaska Department of Fish and Game.
Warmer temperatures caused the metabolism of the fish to speed up, Somerville said. “They need more food for maintenance,” he said. “At the same time, their food source was diminished.”
Other important salmon runs are also struggling, including those in the Kenai River — a world-famous sport fishing site — and along Kodiak Island. Others have had good numbers, though the returning fish are noticeably reduced in size, Somerville said.
In Alaska, where wild salmon is iconic, Copper River fish hold a special status.
Their high oil content is linked to their ultra-long migration route from the ocean to their glacier-fed spawning grounds. They are the first fresh Alaska salmon to hit the market each year. Copper River salmon have sold for $75 a pound.
Chris Bryant, executive chef for WildFin American Grill, a group of Seattle-area seafood restaurants, worries about trends for Alaska salmon beyond the Copper River.
“The fish are smaller, which makes it harder for chefs to get a good yield on it and put it on the plate,” he said.
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From: MeNeedIt
As gigabytes of data flow from field to fingertips, click by click, the technological divide has been closing between teams at the World Cup.
While the focus has been on the debut of video assistant referees, less obvious technical advances have been at work in Russia and the coaches have control over this area, at least.
No longer are the flashiest gizmos to trace player movements and gather data the preserve of the best-resourced nations. All World Cup finalists have had an array of electronic performance and tracking systems made available to them by FIFA.
“We pay great attention to these tools,” Poland coach Adam Nawalka said. “Statistics play an important role for us. We analyze our strength and weaknesses.”
The enhanced tech at the teams’ disposal came after football’s law-making body — on the same day in March it approved VAR — approved the use of hand-held electronic and communications equipment in the technical area for tactical and coaching purposes. That allows live conversations between the coaches on the bench and analysts in the stands, a change from the 2014 World Cup when the information gathered from player and ball tracking systems couldn’t be transmitted in real-time from the tribune.
“It’s the first time that they can communicate during the match,” FIFA head of technology Johannes Holzmueller told The Associated Press. “We provide the basic and most important metrics to the teams to be analyzed at the analysis desk. There they have the opportunity either to use the equipment provided by FIFA or that they use their own.”
The KPI — key performance indicators — fed by tracking cameras and satellites provide another perspective when coaches make judgments on substitutions or tactical switches if gaps exposed on the field are identified.
“These tools are very practical, they give us analysis, it’s very positive,” Colombia coach Jose Pekerman said. “They provide us with insight. They complement the tools we already have. It improves our work as coaches, and it will help footballers too. I think technologies are a very positive thing.”
It’s not just about success in games. Player welfare can be enhanced with high-tech tools to assess injuries in real time allowed for use by medics at this World Cup. Footage of incidents can now be evaluated to supplement any on-field diagnosis, particularly concussion cases.
A second medic “can review very clearly, very concretely what happened on the field, what the doctor sitting on the bench perhaps could not see,” FIFA medical committee chairman Michel D’Hooghe said.
Pekerman is pleased “football is advancing very quickly.” Too quickly, though, for some coaches who are more resistant to the growing role for machines rather than the mind.
“Football is evolving and these tools help us on the tactical and physiological side,” Senegal coach Senegal coach Aliou Cisse said. “We do look at it with my staff, but it doesn’t really have an impact on my decision making.”
Hernan Dario Gomez, coach of World Cup newcomer Panama, has reviewed the data feeds. But ultimately the team has been eliminated in the group stage after facing superior opponents.
“This is obviously very important information, but not more important than the actual players,” Gomez said. “We think first and foremost about the players and the teamwork that is done.”
The data provided on players by FIFA is still reliant the quality of analysts interpreting it.
“You can have millions of data points, but what are you doing with it?” Holzmueller said. “At the end even if you’re not such a rich country you could have a very, very clever good guy who is the analyst who could get probably more out of it than a country of 20 analysts if they don’t know really how they should read the data and what they should do with it.
“So it’s really up to each team and also up to each coach because we realize that for some coaches they say, ‘Look I have a gut feeling … I don’t need this information.’”
FIFA is happy with that. The governing body’s technical staff — the side often eclipsed by the high-profile members of the ruling-council — will continue to innovate.
But artificial intelligence isn’t taking over. For some time, at least.
“People think now it’s all driven by computers,” Holzmueller said. “We don’t want that at FIFA.”
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From: MeNeedIt
Barbie, the world’s most iconic doll, is venturing into coding skills in her latest career as a robotics engineer.
The new doll, launched Tuesday, aims to encourage girls as young as seven to learn real coding skills, thanks to a partnership with the kids game-based computing platform Tynker, toymaker Mattel said.
Robotics engineer Barbie, dressed in jeans, a graphic T-shirt and denim jacket and wearing safety glasses, comes with six free Barbie-inspired coding lessons designed to teach logic, problem solving and the building blocks of coding.
The lessons, for example, show girls how to build robots, get them to move at a dance party, or do jumping jacks.
According to U.S. Department of Commerce statistics, 24 percent of STEM (Science, Technology, Engineering, Math) jobs were held by women in 2017.
Barbie has held more than 200 careers in her almost 60-year life, including president, video game developer and astronaut.
Tynker co-founder Krishna Vedati said in a statement that the company’s mission to empower youth worldwide made Barbie an ideal partner “to help us introduce programming to a large number of kids in a fun engaging way.”
Watch Tynker promotional video:
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From: MeNeedIt
One of the world’s most dreaded viruses has been turned into a treatment to fight deadly brain tumors. Survival was better than expected for patients in a small study who were given genetically modified poliovirus, which helped their bodies attack the cancer, doctors report.
It was the first human test of this and it didn’t help most patients or improve median survival. But many who did respond seemed to have long-lasting benefit: About 21 percent were alive at three years versus 4 percent in a comparison group of previous brain tumor patients.
Similar survival trends have been seen with some other therapies that enlist the immune system against different types of cancer. None are sold yet for brain tumors.
“This is really a first step,” and doctors were excited to see any survival benefit in a study testing safety, said one researcher, Duke University’s Dr. Annick Desjardins.
Preliminary results were to be discussed Tuesday at a conference in Norway and published online by the New England Journal of Medicine.
Making an enemy an ally
Brain tumors called glioblastomas often recur after initial treatment. Immunotherapy drugs like Keytruda help fight some cancers that spread to the brain, but have not worked well for ones that start there.
Polio ravaged generations until a vaccine came out in the 1950s. The virus invades the nervous system and can cause paralysis. Doctors at Duke wanted to take advantage of the strong immune system response it spurs to try to fight cancer. With the help of the National Cancer Institute, they genetically modified poliovirus so it would not harm nerves but still infect tumor cells.
The treatment is dripped directly into the brain through a thin tube. Inside the tumor, the immune system recognizes the virus as foreign and mounts an attack.
When doctors explained the idea to Michael Niewinski, it seemed a feat “like putting a man on the moon,” he said. The 33-year-old from Boca Raton, Florida, was treated last August, and said a recent scan seemed to show some tumor shrinkage.
“I’m pain-free, symptom-free,” he said.
Study results
The study tested the modified poliovirus on 61 patients whose tumors had recurred after initial treatments. Median survival was about a year, roughly the same as for a small group of similar patients given other brain tumor treatments at Duke. After two years, the poliovirus group started faring better.
Follow-up is continuing, but survival is estimated at 21 percent at two years versus 14 percent for the comparison group. At three years, survival was still 21 percent for the virus group versus 4 percent for the others.
Eight of the 35 patients who were treated more than two years ago were alive as of March, as were five out of 22 patients treated more than three years ago.
Stephanie Hopper, 27, of Greenville, South Carolina, was the first patient treated in the study in May 2012 and it allowed her to finish college and become a nurse. Scans as recent as early June show no signs that the tumor is growing, she said.
“I believe wholeheartedly that it was the cure for me,” she said. Her only lasting symptom has been seizures, which medicines help control. “Most people wouldn’t guess that I had brain cancer.”
Side effects
The treatment causes a lot of brain inflammation, and two-thirds of patients had side effects. The most common ones were headaches, muscle weakness, seizure, trouble swallowing and altered thinking skills. Doctors stressed that these were due to the immune response in the brain and that no one got polio as a result of treatment.
One patient had serious brain bleeding right after the procedure. Two patients died relatively soon after treatment — one from worsening of the tumor and the other from complications of a drug given to manage a side effect. The planned doses had to be reduced because there were too many seizures and other problems at the higher doses initially chosen.
One independent expert, Dr. Howard Fine, brain tumor chief at New York-Presbyterian and Weill Cornell Medicine, said it was disappointing to see no improvement on median survival, but encouraging to see “extraordinary responders, a small group of patients who have done markedly better than one would expect.”
The numbers in the study are small, but it’s unusual to see many alive after several years, and suggests the approach merits more and bigger studies, he said.
Next steps
The National Cancer Institute manufactured the modified virus. Federal grants and several charities funded the work. Some study leaders have formed a company that licenses patents on the treatment from Duke.
Duke has started a second study in adults, combining the poliovirus with chemotherapy, to try to improve response rates. A study in children with brain tumors also is under way, and studies for breast cancer and the skin cancer melanoma also are planned.
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From: MeNeedIt
The U.S. Supreme Court on Tuesday struck down a California law that required anti-abortion crisis clinics to let patients know about the availability of free state-provided abortions, ruling that it violated the free-speech rights of the Christian-based centers.
Under a 1973 ruling, abortions are legal in the United States in most instances. But the new 5-4 decision handed anti-abortion activists a significant victory, approving of the way the clinics — often called crisis pregnancy centers — advise women with unplanned pregnancies against having an abortion.
The majority opinion said the California law “imposes an unduly burdensome disclosure requirement” on the clinics to pass on information they do not believe in. California said the law was needed to let poor women know of all options related to their pregnancies.
Justice Clarence Thomas said in his majority opinion that the crisis centers “are likely to succeed” in their constitutional challenge of the law.
Justice Stephen Breyer, writing for four liberal dissenters, said that among the reasons the law should have been upheld is that the Supreme Court had previously ruled in favor of state laws requiring doctors to tell women contemplating an abortion about the availability of adoption services.
“After all,” Breyer wrote, “the law must be evenhanded.”
Crisis centers say they provide legitimate health services for women, but that their mission is to steer women with unplanned pregnancies away from abortion. Abortion rights activists say there are about 2,700 such clinics in the U.S., including 200 in California, far outnumbering the number of clinics that perform abortions.
In 2014, the most recent year for which statistics have been released, the government said 652,639 abortions were performed in the U.S.
U.S. Attorney General Jeff Sessions said the administration of President Donald Trump was pleased that the decision upheld freedom of speech for the clinics.
“Speakers should not be forced by their government to promote a message with which they disagree, and pro-life pregnancy centers in California should not be forced to advertise abortion and undermine the very reason they exist,” Sessions said. He said the Justice Department “will continue to vigorously defend the freedom of all Americans to speak peacefully in accord with their deeply held beliefs and conscience.”
From: MeNeedIt
The group that hands out the Oscars said on Monday that it had invited 928 new members from 59 countries, in its biggest diversity drive after years of criticism of its mostly white and male membership.
Those invited include “Girls Trip” star Tiffany Haddish; “The Big Sick” co-writers Kumail Nanjiani and Emily V. Gordon; and comedian and actor Dave Chappelle, the Academy of Motion Picture Arts and Sciences said in a statement.
If all those invited accept, female membership would rise to 31 percent from the current 28 percent, the group said. People of color will increase to 16 percent from 13 percent.
Total membership would stand at more than 7,000 actors, writers, directors, executives and others.
A lack of diversity within the academy has long been cited as a barrier to racial inclusion in Hollywood’s highest honors.
In 2016, the Academy responded by pledging to double female and minority membership by 2020.
From: MeNeedIt
Malnutrition is the “challenge of our time,” with diet-related disease afflicting almost every country in the world, the winners of a $250,000 prize dubbed the Nobel for agriculture said Monday.
David Nabarro and Lawrence Haddad, who were jointly awarded this year’s World Food Prize, are credited with cutting the number of stunted children in the world by 10 million by lobbying governments and donors to improve nutrition.
Stunting is caused by malnutrition in infancy and hinders cognitive as well as physical growth. Experts say the effects are largely irreversible and stunted children generally complete fewer years of schooling and earn less money as adults.
Malnourished children also tended to become malnourished mothers, perpetuating the cycle, said Haddad, who heads the Global Alliance for Improved Nutrition.
Levels of obesity, diabetes and hypertension were “skyrocketing in pretty much every country … and the center of all these things is diets,” he said.
“People can’t get enough nutritious food because it’s too expensive or unavailable and the stuff that they shouldn’t be eating a lot of, stuff that’s high in sugar, salt and fat, is really cheap and available,” he told Reuters by phone. “This is the big challenge of our time. It’s not about how to feed our world. It’s about how to nourish our world.”
Haddad was joint winner of the award with Nabarro, a British doctor and former U.N. Special Representative for Food Security and Nutrition.
Between them they have persuaded governments, donors and others to set up policies and programs that decreased the number of stunted children globally to 155 million in 2017 from 165 million in 2012, the World Food Prize organizers said.
Nabarro said good nutrition in the first 1,000 days from conception to a child’s second birthday was “absolutely key.”
“There is work still to be done to get a widespread understanding of the importance of the right kind of diet,” he said.
About 815 million of the world’s 7.6 billion people go hungry daily while 2 billion are overweight or obese, according to the U.N. Food and Agriculture Organization.
The winners were honored in a ceremony at the U.S. Department of Agriculture.
Past recipients of the annual prize, founded in 1986 by Nobel laureate Norman Bourlag, include John Kufuour, a former president of Ghana, and Grameen Bank founder and Nobel laureate Muhammad Yunus of Bangladesh.
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From: MeNeedIt
U.S. health regulators on Monday approved the first prescription drug made from marijuana, a milestone that could spur more research into a drug that remains illegal under federal law, despite growing legalization for recreational and medical use.
The Food and Drug Administration approved the medication, called Epidiolex, to treat two rare forms of epilepsy that begin in childhood. But it’s not quite medical marijuana.
The strawberry-flavored syrup is a purified form of a chemical ingredient found in the cannabis plant — but not the one that gets users high. It’s not yet clear why the ingredient, called cannabidiol, or CBD, reduces seizures in some people with epilepsy.
British drugmaker GW Pharmaceuticals studied the drug in more than 500 children and adults with hard-to-treat seizures, overcoming numerous legal hurdles that have long stymied research into cannabis.
FDA officials said the drug reduced seizures when combined with older epilepsy drugs.
The FDA has previously approved synthetic versions of another cannabis ingredient for medical use, including severe weight loss in patients with HIV.
Epidiolex is essentially a pharmaceutical-grade version CBD oil, which some parents already use to treat children with epilepsy. CBD is one of more than 100 chemicals found in marijuana. But it doesn’t contain THC, the ingredient that gives marijuana its mind-altering effect.
Physicians say it’s important to have a consistent, government-regulated version.
“I’m really happy we have a product that will be much cleaner and one that I know what it is,” said Ellaine Wirrell, director of the Mayo Clinic’s program for childhood epilepsy. “In the artisanal products, there’s often a huge variation in doses from bottle to bottle depending on where you get it.”
Side effects with the drug include diarrhea, vomiting, fatigue and sleep problems.
Several years ago, Allison Hendershot considered relocating her family to Colorado, one of the first states to legalize marijuana and home to a large network of CBD producers and providers. Her 13-year-old daughter, Molly, has suffered from severe seizures since she was 4 months old. But then Hendershot learned about a trial of Epidiolex at New York University.
“I preferred this to some of those other options because it’s is a commercial product that has gone through rigorous testing,” said Hendershot, who lives in Rochester, New York.
Since receiving Epidiolex, Hendershot says her daughter has been able to concentrate more and has had fewer “drop” seizures — in which her entire body goes limp and collapses.
FDA warnings
CBD oil is currently sold online and in specialty shops across the U.S., though its legal status remains murky. Most producers say their oil is made from hemp, a plant in the cannabis family that contains little THC and can be legally farmed in a number of states for clothing, food and other uses.
The impact of Monday’s approval on these products is unclear.
The FDA has issued warnings to CBD producers that claimed their products could treat specific diseases, such as cancer or Alzheimer’s. Only products that have received formal FDA approval can make such claims, typically requiring clinical trials costing millions.
Most CBD producers sidestep the issue by making only broad claims about general health and well-being.
Industry supporters downplayed the impact of the FDA approval.
“I don’t know a mom or dad in their right mind who is going to change what’s already working,” said Heather Jackson, CEO of Realm of Caring, a charitable group affiliated with Colorado-based CW Hemp, one of nation’s largest CBD companies. “I really don’t think it’s going to affect us much.”
Cost
Jackson’s group estimates the typical family using CBD to treat childhood epilepsy spends about $1,800 per year on the substance.
A GW Pharmaceuticals spokeswoman said the company would not immediately announce a price for the drug, which it expects to launch in the fall. Wall Street analysts have previously predicted it could cost $25,000 per year, with annual sales eventually reaching $1 billion.
For their part, GW Pharmaceuticals executives say they are not trying to disrupt products already on the market. The company has pushed legislation in several states to make sure its drug can be legally sold and prescribed.
The FDA approval for Epidiolex is technically limited to patients with Dravet and Lennox-Gastaut syndromes, two rare forms of epilepsy for which there are few treatments. But doctors will have the option to prescribe it for other uses.
The new medication enters an increasingly complicated legal environment for marijuana.
Nine states and the District of Columbia have legalized marijuana for recreational use. Another 20 states allow medical marijuana, but the U.S. government continues to classify it as a controlled substance with no medical use, in the same category as heroin and LSD.
Despite increasing acceptance, there is little rigorous research on the benefits and harms of marijuana. Last year a government-commissioned group concluded that the lack of scientific information about marijuana and CBD poses a risk to public health.
Before sales of Epidiolex can begin, the Drug Enforcement Administration must formally reclassify CBD into a different category of drugs that have federal medical approval.
GW Pharmaceuticals makes the drug in the U.K. from cannabis plants that are specially bred to contain high levels of CBD. And the company plans to continue importing the medicine, bypassing onerous U.S. regulations on manufacturing restricted substances.
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From: MeNeedIt
The 2018 BET Awards barely handed out any trophies with big stars like Cardi B, Drake and Kendrick Lamar absent, but the show included superior performances by rising singer H.E.R., rapper Meek Mill and gospel artist Yolanda Adams, who paid tribute to Anita Baker and nearly brought her to tears.
Baker, an eight-time Grammy winner who dominated the R&B charts from the early ’80s to mid-90s, earned the Lifetime Achievement Award on Sunday at the Microsoft Theater in Los Angeles.
The 60-year-old used her speech to encourage the artists in the room to keep music alive.
“I would ask that the music be allowed to play, that singers are allowed to sing, and rappers are allowed to rap, and poets are allowed to rhyme,” said Baker, who also was honored by host Jamie Foxx, Ledisi and Marsha Ambrosius.
H.E.R., whose real name is Gabi Wilson, was impressive as she sang the R&B hit “Focus,” played the electric guitar like a rock star and sang softly during the sweet love song “Best Part,” where she was joined by Daniel Caesar.
Meek Mill, who was released from prison in April, rapped the song “Stay Woke” on a stage transformed into a street corner, featuring hustlers, children and police officers. A mother screams as her child is shot during the powerful performance, and an officer lays an American flag over the body.
Meek Mill also made a statement by wearing a hoodie featuring the face of XXXTentacion, the 20-year-old rapper-singer who died after being shot last week.
“We can’t get used to these types of things. We’re too used to young people getting killed,” Foxx said when speaking about XXXTentacion later in the show.
The Oscar winner told the audience to “try to sneak a message in” their music.
“We got to figure something out,” he said.
Snoop Dogg celebrated 25 years in music, performing the classic songs “What’s My Name” and “Next Episode.” The rapper also performed songs from his recently released gospel album, wearing a choir robe on a stage that looked like a church.
Childish Gambino, whose song and music video “This Is America” tackles racism and gun violence and became a viral hit last month, gave a short, impromptu performance of the song when Foxx brought him onstage.
“Everybody begged me to do a joke about that song. I said that song should not be joked about,” Foxx said.
Foxx kicked off the show rejoicing in the uber success of “Black Panther,” namedropping the records the film has broken and even pulled Michael B. Jordan onstage to recite a line from the film.
“We don’t need a president right now because we got our king,” Foxx said of T’Challa. “(Director) Ryan Coogler gave us our king.”
Foxx entered the arena with a stuffed black panther toy – with a gold chain around its neck – which he handed to Jordan. The film won best movie.
“The film is about our experiences being African-Americans and also captures the experiences of being African,” Coogler said. “It was about tapping into the voice that tells us to be proud of who we are.”
At the end of his speech he told the audience to travel to Africa and learn more about the continent’s history.
SZA, who was the most nominated woman at this year’s Grammys, won best new artist and said she’s “never won anything in front of other people.”
She dedicated the award to those “lost in the world,” saying: “Follow your passion … believe in yourself.”
After the show, BET announced that Kendrick Lamar had won best album for “DAMN.” and best male hip-hop artist. Beyonce won best female pop/R&B artist, while Bruno Mars was named the best male pop/R&B artist.
“Girls Trip” star and comedian Tiffany Haddish, who won best actress and gave her speech in a taped video, also said encouraging words.
“You can achieve anything you want in life,” she said.
DJ Khaled was the leading nominee with six and picked up the first award of the night – best collaboration – for “Wild Thoughts” with Rihanna and Bryson Tiller. He was holding his son on his hip onstage and also used his speech to highlight young people.
“All of y’all are leaders and all of y’all are kings and queens – the future,” he said.
Migos won best group and gave a fun performance that even had Adams reciting the lyrics. J. Cole, Nicki Minaj, Janelle Monae, Miguel, YG, 2 Chainz and Big Sean also performed.
The BET Awards normally hands its Humanitarian Award to one person, but six individuals received the honor Sunday. Dubbed “Humanitarian Heroes,” the network gave awards to James Shaw Jr., who wrestled an assault-style rifle away from a gunman in a Tennessee Waffle House in April; Anthony Borges, the 15-year-old student who was shot five times and is credited with saving the lives of at least 20 other students during February massacre in Florida; Mamoudou Gassama, who scaled an apartment building to save a child dangling from a balcony last month in Paris; Naomi Wadler, an 11-year-old who gave a memorable and influential speech at March for Our Lives; Justin Blackman, the only student to walk out of his high school in North Carolina during the nationwide student walkout to protest gun violence in March; and journalist and activist Shaun King.
Debra Lee, who stepped down as chairman and CEO of BET last month after 32 years at the network, earned the Ultimate Icon Award.
“The power of black culture is unmatched. It’s beautiful. It’s amazing. It’s everything. It’s us,” she said.
She ended her speech quoting former U.S. President Barack Obama, calling him “our commander in chief,” which drew loud applause.
“And, it’s Debra Lee, out,” she said as she dropped her imaginary microphone.
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From: MeNeedIt