In 1995, a patient sick with the Ebola virus, in what was then called Zaire and is now the Democratic Republic of the Congo, miraculously recovered from this deadly disease. At that time, when the virus first jumped from animals to man, Ebola meant almost certain death.

Doctors found that this patient had antibodies to fight the virus in his bloodstream even after he recovered. 

Dr. Anthony Fauci, head of the National Institute of Allergy and Infectious Diseases at the National Institutes of Health, invited the patient to the U.S., where researchers cloned the cell that had helped him beat Ebola.

“We brought the person back to the United States to draw his blood and try to clone the B cells that make the antibodies that this person had produced … to then, essentially, clear his virus and, hopefully, protect him against any future exposure,” Fauci told VOA. 

Because the NIH scientists made numerous copies of that cell, it is called a monoclonal antibody — in this case, mAB114. It’s hoped that it can be used to target the Zaire strain of Ebola currently spreading in eastern Congo.

Fauci said mAB114 is still experimental.

“We have done a number of tests in an animal model and have shown that when you infect an animal up to five days after they become infected, and you passively transfer this antibody, you can actually protect the animals from getting sick and they recover,” he said.

Not all treatments that work in animals work in humans, something Fauci knows all too well. One treatment for HIV/AIDS that Fauci found worked well in monkeys had disastrous effects when tested in humans.

Fauci’s staff is conducting a phase one clinical trial in volunteers at the NIH hospital to make sure mAB114 is safe. So far, no one can say whether the treatment works, but because of the dire situation in Congo, and the fear the virus will spread in the armed conflict that is going on in the region, Fauci said the antibody has been given to five people with Ebola.

At a news conference Tuesday, Dr. Tedros Adhanom Ghebreyesus, director-general of the World Health Organization, said he had been told they were doing well.

As of now, there’s no approved treatment for the disease, although there is a vaccine that protects people who may have been exposed to the virus but who are not sick. 

Other experimental treatments are also being used to help end the outbreak in Congo. One of them is ZMapp, a combination of three monoclonal antibodies. In 2016, NIH found ZMapp safe and well-tolerated, but without an outbreak, it is impossible to prove effectiveness. 

Fauci said another antiviral drug, remdesivir, is being used in patients with Ebola from West Africa, even though that outbreak is over. Scientists have found the Ebola virus can remain in the semen, so men are being treated to prevent further spread.

Remdesivir, or GS-5734, is produced by Gilead. On its website, Gilead says remdesivir is thought to work by blocking a key enzyme the virus needs to reproduce itself. Tomas Cihlar, Gilead’s vice president for biology, is quoted as saying, “Based on animal studies, we believe that the compound is able to penetrate the organs and tissues throughout the body where Ebola replicates.”

So far, there are no proven treatments for Ebola. Scientists are hopeful that that therapeutic antibodies could be the best way to stop this virus. An international study led by Scripps Research suggests that antibodies may be valuable treatments against new viruses and could help a patient’s immune system fight the Ebola virus after being infected.
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From: MeNeedIt

Oscar-winning British actress Emma Thompson, now starring at age 59 as a family court judge in the dramatic movie “The Children Act,” said on Thursday that older women still need more opportunity on the big screen.

Known for period dramas such as “Howards End” and “Sense and Sensibility,” Thompson plays a judge who struggles with a legal decision while also dealing with trouble in her marriage.

At the movie’s red-carpet premiere, Thompson said she was drawn to the role of a woman who has gained power in “a very male bastion.”

“I’d never seen a story about a female judge, and I think in our patriarchal world, when you hear the word judge, you automatically think, ‘Oh, it’s a man,’” Thompson said.

She also said the lack of good film roles for older women remains a long-running problem.

“Men don’t have any problem with that,” Thompson said. “It’s something that hasn’t yet properly changed.

“We are seeing some really good and interesting new roles, so one’s got to be hopeful,” she added.
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From: MeNeedIt

Scientists in Florida are on the cusp of developing promising methods to control toxic algae blooms like the “red tide” that has been killing marine life along a 150 mile (240 km) stretch of the Gulf Coast, the head of a leading marine lab said Wednesday.

Michael Crosby, president and chief executive of the Mote Marine Laboratory in Sarasota, welcomed a red tide emergency order issued this week by Governor Rick Scott, designating more state money for research, cleanup and wildlife rescues.

Scientists field-testing solutions

Interest in mitigation technologies has been heightened by a 10-month-long toxic algae bloom off Florida’s southwestern coast that has caused mounds of rotting fish to wash up on beaches from Tampa to Naples.

The red tide also has been implicated in at least 266 sea turtle strandings and is suspected or determined to have caused 68 manatee deaths so far this year, according to Florida Fish and Wildlife Conservation Commission figures.

In hopes of combating future outbreaks, scientists are field testing a patented process that would pump red-algae-tainted seawater into an ozone-treatment system and then pump the purified water back into the affected canal, cove or inlet, Crosby said.

Experiments carried out in huge 25,000-gallon tanks succeeded in removing all traces of the algae and its toxins, with the water chemistry reverting to normal within 24 hours, he said.

Scientists also are studying the possible use of naturally produced compounds from seaweed, parasitic algae and filter-feeding organisms that could be introduced to fight red tides.

A ‘bad bloom’

Red tides occur on an almost yearly basis off Florida, starting out in the Gulf of Mexico where swarms of microscopic algae cells called Karenia brevis feed on deep-sea nutrients and are sometimes carried by currents close to shore, usually in the fall.

This year’s Gulf Coast Florida bloom is the worst in more than a decade, originating last October and persisting well into the summer tourist season while spreading across 150 miles of coastline spanning seven counties.

“It’s a bad bloom by any standard,” said Richard Stumpf, an oceanographer who studies red tides for the National Oceanic and Atmospheric Administration (NOAA).

For reasons not well understood, strong northerly winds that normally break up a red tide by December failed to materialize last winter, Stumpf said.

It remains to be seen whether a single year of altered wind patterns will turn out to be an isolated deviation or part of more long-term changes in climate, Stumpf said.

Natural phenomenon

But scientists say red tides in and of themselves are a natural phenomenon observed as far back as the 1600s.

For humans, exposure can cause respiratory difficulties, burning eyes and skin irritation. The toxins are often fatal to marine life.

The latest bloom coincided with the spawning season for snook, an ecologically important and popular game fish in Florida, Crosby said. A portion of emergency funding ordered by the governor is earmarked for assessing impacts on that fish.
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From: MeNeedIt

Singapore is the setting for new Hollywood movie ‘Crazy Rich Asians’ – an adaptation of a best-selling novel that explores the insatiable consumerism of new money and old-world opulence in a continent producing more billionaires than anywhere else.

While the low-tax financial hub is often called a playground for the rich, Singapore’s wealthy tend to live a more conservative, low-key life than Hong Kong’s showy socialites or Macau’s high-rollers.

In step with the film’s release in the United States on Wednesday and ahead of its release in the city-state next week, here are five ways to spend your cash in Singapore.

1. Orchid-shaped supercars

Cars in Singapore are some of the most expensive in the world, owing to huge government taxes aimed at limiting their number in the tiny island-state.

That doesn’t stop the super-rich – Ferrari, Maserati and Lamborghini are commonly sighted. When a Singaporean character in Kevin Kwan’s book, Goh Peik Lin, moves to America to study she immediately buys a Porsche saying they are “such a bargain.”

For the super-rich patriot, Singapore-based firm Vanda Electrics has designed an electric supercar – Dendrobium. Its roof and doors open in sync to resemble the orchid that is native to Singapore and after which the vehicle is named.

A show car, built by the technology arm of the Williams Formula One team, was unveiled last year. It was originally estimated to cost around 3 million euros ($3.44 million) before tax, although Vanda Electrics advised the final price will likely be lower.

2. Yachts with submarines

Yachts are an affordable alternative to such supercars.

“Impulse buys of luxury items such as yachts are becoming more common” said Phill Gregory, the Singapore head of yacht dealers Simpson Marine, who sell everything from sports boats to super yachts costing tens of millions of dollars.

Gregory said Singapore-based clients have some of the most sophisticated tastes and an eye for style: sometimes he flies them to Europe to deck out their yacht with luxury furniture from the artisans of Milan or world-famous Carrara marble straight from the quarries in Tuscany.

Others have more unusual requests. These include a bespoke ‘beach club style’ lounge area set underneath a shimmering swimming pool, helipads or even a space to park a small submarine or sea-plane.

3. 999 roses

The iconic Marina Bay Sands hotel – which resembles a giant surfboard perched on three tall columns – features prominently in the film’s trailer.

The hotel features the invitation-only Chairman’s suite – the largest in Singapore – which has its own gym, hair salon, and karaoke room, and according to some media reports costs over $15,000 a night. There is no publicly available price.

The likes of former British soccer star David Beckham and Bollywood actor Shah Rukh Khan have stayed at the hotel.

George Roe, director of hotel operations at Marina Bay Sands, said he has had some unusual requests from his guests including organizing the delivery of 999 roses to a residential address in Singapore as a surprise.

4. Rare beef

“You do realize Singapore is the most food obsessed country on the planet?,” Nick Young, the very well-heeled protagonist of ‘Crazy Rich Asians’ tells his girlfriend Rachel Chu ahead of their trip to the city-state.

Even hawker stalls hold Michelin stars in Singapore but there’s no shortage of places for the super-rich to get their fix.

The restaurant CUT by Wolfgang Puck is the only one in Singapore to offer Hokkaido snow beef – which is even scarcer than Kobe beef – through an exclusive arrangement with a private reserve in Japan.

Only two cattle are harvested from the reserve every month, with CUT receiving about 20-30 steaks a month – a chunk of which goes to regulars who visit the restaurant every time it comes on the menu, said general manager Paul Joseph. The current price is S$330 ($240) for a modest 170 gram serving.

5. Gold tea

Forget wearing gold – in Singapore you can drink it. 

Boutique Singaporean tea company TWG Tea claims to sell one of the world’s most expensive teas – a white tea plated with 24-karat gold which retails at S$19,000 ($14,000) a kilo.

The Grand Golden Yin Zhen is described as a “glimpse of the divine in a teacup”, and the gold is said to have anti-oxidant properties that revitalize and rejuvenate the skin.
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From: MeNeedIt

The diversity crisis in Hollywood may rage on, but the Academy of Motion Picture Arts and Sciences continues to try to open up access to the entertainment business for people from underrepresented communities and give some a foot in the door at the most critical moment — when college graduation is in sight and the job market is looming.

For seven weeks this summer, 107 college students from across the nation convened in Los Angeles for internships at places like HBO, Warner Bros., Dolby Laboratories, Universal Pictures, IMAX and AMC Networks, in addition to film screenings and weekly panels on various aspects of the film industry from people at the top of their fields.

Notable speakers this summer included cinematographer Janusz Kaminski (Schindler’s List), production designer K.K. Barrett (Her), Sorry to Bother You director Boots Riley and actress Lily Collins, who dished on the casting process. Cinematography and production design students even got to work with Daryn Okada, an academy governor, to recreate a scene from Mean Girls, which Okada shot.

The program, now in its second year, continues to evolve. In addition to giving spots to more than 30 additional students, this year Academy Gold added a Production Track program for students interested in cinematography, production design, post-production and film editing.

Statistics dire for most

The statistics remain dire in the entertainment business job market for anyone who isn’t a white, straight, able-bodied male. A survey from the Center for the Study of Women in Television and Film found that of the top 100 grossing films of 2017, 2 percent had female cinematographers and 14 percent had female editors. And according to the University of Southern California’s Annenberg Inclusion Initiative, across 1,100 of the top grossing films over the past decade, 64, or 5.2 percent, had black directors and 38, or 3.1 percent, had an Asian or Asian-American director.

Academy Gold is an industrywide effort to infuse the entertainment business with diverse talent at the early stages of a career. The film academy, which puts on the Oscars, has been criticized in the past for the lack of diversity in its membership ranks, and has been making strides to correct that in the past two years. In addition to inviting new members with an eye toward inclusion, the Academy Gold program is addressing the issue at an earlier stage.

Academy Gold wrapped its summer program this past weekend and sent its second class of alumni back to finish their college educations armed with a designated mentor for eight months, contacts, peers and even a few new career ideas.

“A lot of students who came in thinking they wanted to do one thing have said, ‘You know what I think I might be interested in cinematography or editing,’” said Bettina Fisher, the academy’s director of educational initiatives.

First-hand experience

Tatianna Sims, a 21-year-old New York University student from New Jersey, interned this summer with Marvel Studios in the VFX and post-production department.

“The greatest thing about this program is hearing about first-hand experiences from people who have amazing careers,” said. “From the outside, it looks like this gilded place where no one can enter, but when speaking with a lot of the panelists you see how achievable a lot of your goals are.”

Twenty-six entertainment businesses funded the program, which not only ensures that interns are paid, but also provides stipends for more than 30 students to help with living expenses. It proved “life-changing” for Vaughn Arterberry, a 22-year-old aspiring director from Oakland, Calif, who interned in production and development at Focus Features this summer before he starts at the University of Southern California Film School in January.

“I wouldn’t have been able to afford to live in LA this summer without some help financially,” Arterberry said before a panel on film financing and distribution. “I’m extremely grateful for what they’ve done.”

Benefits apparent

Some alumni are seeing the benefits of their Academy Gold experience and the mentorship with a film academy member that follows.

Jordan Moss, who interned in the accounting department of Paramount Pictures in its pilot year and aspires to be in animated feature development, said he’s most grateful for the peers he met.

“I believe that these are the people who are going to be running the industry some day,” Moss said.

Program administrators want to start tracking the development of their alumni as they hopefully get jobs and rise in the industry.

“We have made significant progress and we look forward to pushing this program forward and expanding it to more students in the future,” said Edgar Aguirre, the academy’s director of talent development and inclusion. “At the end of the day, this is going to be an opportunity to guide and develop the next generation of leadership in this industry.”
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From: MeNeedIt

One American university is putting electronic voice-controlled assistants in every student housing room on campus.

Saint Louis University recently announced it will equip every student living space with Amazon’s Alexa system. The school in St. Louis, Missouri, will place about 2,300 Echo Dot “smart” devices in all student dorms and other university housing.

Officials said the university will be the first in the world to put the devices in every student living space. The devices and the Alexa service are being provided at no costs to students.

The Amazon Echo is a speaker with the ability to listen and “talk” to users and can perform some operations. The Alexa assistant competes with similar systems made by Google and Apple.

Devices linked to the systems have become increasingly popular in homes in recent years. They can be used for things like looking up information, playing music, ordering food or buying things on the internet. The devices can also complete actions in the home. These include turning lights on and off, and controlling systems for heating and cooling and security.

Amazon calls these different tasks Alexa can perform “skills.”

Amazon said in a website post that Saint Louis University chose the Alexa system after carrying out a test program. The program involved the Echo Dot and a device from a competing company. It said the students had a better reaction to the Alexa system.

The Echo Dots will include a special skill developed especially for Saint Louis University. It will provide information and answer questions about local school activities and campus life.

Next year, the university plans to add more personalized skills, such as providing information about classes and grades.

The university said it did not increase student tuition to pay for the project. Instead, officials said, it was financed through the school’s general fund, as well as partnerships with Amazon and n-Powered.  The company, based in Los Angeles, California, helped develop the parts of the system that are related to Saint Louis University.

David Hakanson is Saint Louis University’s vice president and chief information officer. In announcing the project, he said it will fit well with students who are “highly driven to achieve success in and out of the classroom.”

He added: “Every minute we can save our students from having to search for the information they need online is another minute that they can spend focused on what matters most: their education.”

While the devices are being placed in every university housing space, students do not have to use them. For those wishing not to take part, the school suggests students just remove the devices from their rooms and put them away in a safe place.

Other universities have also experimented with voice-controlled assistants in student living areas.

A year ago, Arizona State University announced a program that provided Echo Dot devices to a special housing area for engineering students. In the program, all engineering students moving into the special housing community were given the choice of receiving an Echo Dot if they wanted one.

As is the case at Saint Louis University, Arizona State students are able to use the system to get the latest information on university programs and events. However, the Arizona students also have the chance to sign up for classes that teach subjects related specifically to creating new uses for Alexa devices.

Octavio Heredia is a director with Arizona State’s Fulton Schools of Engineering. He said he thinks it is a good idea for students to get as much experience as possible with the voice assistants to improve their development skills and prepare for future jobs.

“Once they are familiar with the devices, they are going to want to further develop their own skills and begin integrating that technology – the hardware and the skills – into other projects,” he said.
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From: MeNeedIt

How do you know if a piece of art is real or fake? Ask a scientist. At New York’s Metropolitan Museum of Art, chemistry, physics and geology are all playing a part in the detective work of determining whether a work of art is original or a forgery. Now teens are learning the tricks of that trade as well. Tina Trinh has more.
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From: MeNeedIt

Only four ingredients are needed to make one of the oldest staples of mankind. Mix water, hops, malt and yeast and you’re well on your way to making beer. But as Sadie Witkowski reports, it’s the smallest ingredient in beer that’s making the biggest splash.
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From: MeNeedIt

Tesla’s board named a special committee of three directors on Tuesday to evaluate possibly taking the electric carmaker private, although it said it had yet to see a firm offer from the company’s chief executive, Elon Musk.

The Silicon Valley billionaire last week said on Twitter he wants to take Tesla private at $420 a share, valuing it at $72 billion, and that funding was “secured.”

That earlier tweet triggered investor lawsuits and an investigation by the U.S. Securities and Exchange Commission into the accuracy of his statement, according to multiple media reports.

Musk on Monday gave his most detailed vision of how a take-private deal could work, but shares ended flat, indicating investor skepticism.

The shares were last down 1 percent at $352.88 on Tuesday.

Musk said Monday he had held talks with a Saudi sovereign fund on a buyout that would take Tesla off the Nasdaq exchange – an extraordinary move for what is now the United States’ most valuable automaker. Tesla has a market capitalization of $60 billion, bigger than Detroit rivals General Motors Co or Ford Motor Co, who produce far more cars.

The company said in the statement the special committee has the authority to take any action on behalf of the board to evaluate and negotiate a potential transaction and alternatives to any transaction proposed by Musk.

Tuesday’s announcement means three members of Tesla’s board will now weigh whether it is advisable – or even feasible – to pursue what could be the biggest-ever go-private deal, and they are doing so before receiving a formal proposal from the CEO.

“The special committee has not yet received a formal proposal from Mr. Musk regarding any Going Private Transaction,” the company said in a public filing with U.S. securities regulators, the first it has made since Musk’s tweets last week.

Asked about the outcome of the special committee, analyst Chaim Siegel at Elazar Advisors said, “This is not easy. Anything is possible from pulling something together to nothing. I hope nothing – so the stock can trade and benefit from the earnings inflection,” he said, referring to a promise by Musk the company would turn profitable later this year.

A blogging, tweeting CEO

Musk has yet to convince Wall Street analysts and investors that he can find the billions needed to complete the deal. Tesla’s handling of Musk’s proposal and its failure to promptly file a formal disclosure, meanwhile, have raised governance concerns and sparked questions about how companies use social media.

Musk first tweeted he planned to go private and that funding was “secured” last week, sending Tesla shares soaring 11 percent, but investors have appeared skeptical about the details he has provided since.

He blogged on Monday that recent talks with a Saudi sovereign wealth fund gave him confidence funding was nailed down, but that he was still talking with the fund and other investors. He tweeted later he was working with Goldman Sachs Group Inc and Silver Lake as financial advisers, though a source said the private equity firm was working in an unpaid, informal capacity and also not discussing participating as an investor.

Goldman had not been formally tapped as a financial adviser by Musk when he revealed plans last week to take the automaker private and said he had secured the funding for the transaction, Bloomberg reported on Tuesday, citing people with knowledge of the matter.

Goldman did not respond to a request for comment from Reuters.

“Despite Elon Musk’s frustration with being a public company, I think there are more advantages to remaining public,” said CFRA analyst Efraim Levy, citing cheaper access to capital and media exposure due to interest in a public company.

Three-member panel

Tesla said the committee consists only of independent directors: Brad Buss, Robyn Denholm and Linda Johnson Rice.

But corporate governance and shareholder voting advisers Glass Lewis and Institutional Shareholder Services said they do not consider Buss an independent director, due to his connections to a solar panel business the company bought two years ago.

Buss was chief financial officer of solar panel installer SolarCity for two years before retiring when Tesla paid $2.6 billion for the sales and installation firm in 2016. It was Tesla’s last big deal and was criticized by some on Wall Street because the company, founded by two of Musk’s cousins, had seen its business shrink before the takeover.

Denholm, the first woman on Tesla’s board, is chief operations officer of telecom firm Telstra and the ex-CFO of network gear maker Juniper Networks.

Rice, the first African-American and second woman to join the board, is CEO of Johnson Publishing Company and Chairman Emeritus of EBONY Media Holdings, the parent of EBONY and Jet brands, according to Tesla’s website.

Tesla’s other board members include Musk; his brother Kimbal Musk; Twenty-First Century Fox’s CEO James Murdoch; Antonio Gracias, founder of Valor Equity Partners; and Ira Ehrenpreis, founder of venture capital firm DBL Partners.

One director, Steve Jurvetson, is currently on leave of absence following allegations of sexual harassment.

Tesla’s board said on Aug. 8 that Musk had held talks with the directors in the previous week on taking the company private.

Latham and Watkins LLP has been retained by the committee as its legal counsel. Wilson Sonsini Goodrich and Rosati will be legal counsel for Tesla itself.

 
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From: MeNeedIt

World Health Organization chief, Tedros Adhanom Ghebreyesus says the raging conflict in North Kivu makes the Ebola outbreak in eastern DR Congo more dangerous than the historic 2014-2015 epidemic in West Africa.  More than 11,000 people died from the Ebola virus by the time it was contained in 2016. 

WHO Director-General Tedros returned Sunday from a visit to Beni and Mangina, the epicenters of the Ebola outbreak in eastern Democratic Republic of Congo.  He says he was worried before he went on this mission, but he is more worried now after having observed first-hand the dangers and difficulties posed by the active conflict in North Kivu.

He says more than 100 armed groups operate in the region.  He says there have been 120 violent incidents this year involving killings, kidnappings, rapes and other atrocities.

“That environment is really conducive for Ebola actually to transmit freely because in that area there are places called Red Zones, inaccessible areas because there are many armed groups that operate in that region … And, these Red Zones could be hiding places for Ebola,” said Tedros.

Tedros is calling on the warring parties for a cessation of hostilities, warning this extremely contagious virus is dangerous for everyone.  Despite the many concerns, he says WHO and partners are moving ahead aggressively with the operation to contain this deadly virus.  

He says more than 216 health workers and 20 people from the community have been vaccinated against Ebola.  He says more vaccinators have been deployed from Guinea to speed this process along, and DRC authorities have given the greenlight for the use of several experimental Ebola drugs.

Tedros says health workers have begun working on case identification and contact tracing, as well as community outreach and educational programs.  He says WHO is working with countries neighboring DRC, and is helping Uganda, Burundi, Rwanda and South Sudan strengthen their surveillance and screening programs to try to prevent the deadly Ebola virus from crossing their borders.  

 
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From: MeNeedIt

Forty-one people have died in the latest outbreak of Ebola in DRC, health authorities said on Tuesday, adding that doctors were using a novel drug to treat patients.

Out of 57 recorded cases as of Monday, 41 were fatal, the Congolese Health Ministry and UN’s World Health Organization (WHO) said. Fourteen of the deaths had been confirmed by lab tests, the ministry said.

Last Friday, the ministry put the tally at 37 deaths, either confirmed or suspected.

The outbreak is the country’s 10th since 1976, when the disease was first identified in the Democratic Republic of Congo (DRC) near the Ebola River, a tributary of the Congo.

Its epicenter is Mangina in the region of Beni, in the strife-torn eastern province of North Kivu.

For the first time since the outbreak was announced on August 1, one fatality was recorded outside of North Kivu — in the neighboring province of Ituri, the ministry’s directorate for disease control said.

It added that doctors in Beni had started to use a novel treatment called mAb114 to treat patients with Ebola.

The treatment is “the first therapeutic drug against the virus to be used in an active Ebola epidemic in the DRC,” it said.

Developed in the United States, the prototype drug is a so-called single monoclonal antibody — a protein that binds on to a specific target of the virus and triggers the body’s immune system to destroy the invader.

The antibody was isolated from a survivor of an Ebola outbreak in the western DRC city of Kikwit in 1995, it said.

In May, the US National Institute of Allergy and Infectious Diseases (NIAID) said it was carrying out the first human trials of mAb114 to test it for safety and tolerance.

Fighting could hamper treatment

Use of the experimental treatment in the field comes on the heels of deployment of an unlicensed vaccine in an earlier outbreak of Ebola in the DRC this year.

The decision to use the vaccine, called rVSV-ZEBOV, came after trials during a pandemic in West Africa showed it to be safe and effective, the WHO says.

Immunization with rVSV-ZEBOV was given to front-line health workers to provide them with additional protection — a tactic that has been repeated in the latest outbreak.

Ebola causes serious illness including vomiting, diarrhea and in some cases internal and external bleeding. It is often fatal if untreated.

The WHO has expressed concern that the violence in North Kivu — entailing militias who often fight for control of resources, including a notorious Ugandan rebel force called the Allied Democratic Forces (ADF) — could hamper the fight against the new outbreak.

WHO Director General Tedros Adhanom Ghebreyesus, visiting the area, on Sunday called for “free and secure access” for health workers, the agency said in a statement.

The outbreak in North Kivu was declared a week after WHO and the Kinshasa government hailed the end of a flareup in northwestern Equateur province which killed 33 people.

In the worst Ebola epidemic, the disease struck the West African states of Guinea, Liberia and Sierra Leone in 2013-15, killing more than 11,300 people.

 
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From: MeNeedIt

Constance Wu had resigned herself to the fact that “Crazy Rich Asians” was not going to work out for her. She was under contract for her sitcom “Fresh Off the Boat,” both were filming in the fall, and that was that. “Crazy Rich Asians” would be the first studio-made Asian-American movie in 25 years, and Wu, who has established herself as a crusader for Asian-American representation in Hollywood, would have to sit this historic moment out.

But then, feeling “kind of dramatic,” and thinking about the significance of the project to her and untold number of Asian-Americans who make it a point to tell her their stories because of her tweets and “Fresh Off the Boat,” Wu decided to give it one last shot and composed an email to “Crazy Rich Asians” director Jon M. Chu.

“I said, I know the dates don’t work out and whoever you cast, I will be the first in line and I will be their No. 1 fan and supporter, but I did want to let you know that I would put 110 percent of my heart into this project and I know what to do with it and how to carry a movie and if you can just wait for me, I don’t think you’ll regret it,” Wu, 36, said. “I did NOT think this email would work. I did it more for me so that I felt that I had told my truth. But then he read it and said, “You guys, we’ve got to push the production.”

Sitting in a restaurant at the Beverly Wilshire, a hotel famous for co-starring in another “Cinderella” story, “Pretty Woman,” and sipping on a “cocktail” of grapefruit juice and sparkling water, Wu is describing how “Crazy Rich Asians,” out nationwide Wednesday is also a kind of “Cinderella” story. Based the first book in author Kevin Kwan’s popular trilogy, Wu’s character Rachel Chu is a middle-class economics professor from the U.S. who finds herself navigating the upper echelons of Singapore’s wealthy classes when her boyfriend Nick Young takes her home for a wedding and to meet his disapproving family and all the jealous women also vying for the attention of the “prince.”

“It’s a fairy tale, it really is,” Wu said. “And there are a lot of different shoes in the movie!”

A native of Richmond, Virginia, and a classically-trained theater actress with a passion for musicals, Wu has been working toward a moment like this her whole life, and taking it very seriously. During the shoot, she wouldn’t go out with her co-stars for karaoke nights or have a drink after a long day of work. She wanted to be clear of mind and she’d already promised her director that she was going to give it her all.

She knew how unlikely it was that she’d ever get an opportunity as an Asian-American woman to lead a studio movie.

“Even a terrific actress like Sandra Oh was always No. 2 or No. 3 in the movie, she was never No. 1 unless it was an independent movie,” said Wu, who is not shy about saying that she only wants to go out for roles where she is the No. 1 star. It’s a drive that has made some uncomfortable.

“People are like, ‘Who do you think you are?’ And it’s like, I guess I think I’m a talented actor and I guess I’m not a person who is going to let you make me feel small anymore,” she said.

But Wu isn’t interested in making people feel comfortable at the expense of her truth, which is why at least part of her time is spent amplifying underrepresented voices on twitter, even knowing that it’s affected her employment opportunities.

Wu once heard that a friend’s liberal boyfriend said he didn’t like Wu’s politics.

“I’m like, ‘Does he not like my politics or does he not like that I have politics?’ And she asked him and he was like, “Oh I guess it’s that,’” Wu said.

Fame, she said, is silly in that regard. She thinks it’s “dumb” that she has a bigger voice than other people, like journalists or academics who are more studied in discourse on race and intersectionality. But, she also realized that while she has this platform, she can at least do some good with it.

Henry Golding, who plays Nick, is in awe of Wu’s fortitude.

“She’s such a role model for so many people. She has a backbone, which a lot of people don’t. She’s not afraid of saying what’s on her mind and really driving home what she thinks should be done, or what’s not happening in the industry that should be happening,” said Golding. “She’s going to go down as a real fighter and someone who can act the socks off anything. She is Rachel Chu.”

As for what’s next, Wu said she thinks she’s going to have a lot of choices in the coming years.

“I’m very privileged and lucky and I’m at a point where I can sort of get to decide where I want to go with my career,” Wu said.

And first up on her wish-list? A musical.
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From: MeNeedIt